PMID- 32261134 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200408 IS - 2050-7518 (Electronic) IS - 2050-750X (Linking) VI - 1 IP - 31 DP - 2013 Aug 21 TI - Charge sensing by organic charge-modulated field effect transistors: application to the detection of bio-related effects. PG - 3811-3819 LID - 10.1039/c3tb20237b [doi] AB - The ability of field effect transistors (FETs) to detect charge variations on the gate may be exploited for realizing chemo- and bio-sensors. In this paper, we focus our attention on a particular kind of field effect device, named organic charge modulated FETs, whose features can be optimized for charge detection in liquid solutions. The results of the measurement of different bio-related effects are shown. In particular, DNA hybridization and pH detection in liquid media are proposed. Finally, preliminary considerations about the applicability of these devices to the detection of the electrical activity of cells are also provided. The device has considerable potential for being employed as a reliable, high sensitivity, low cost technology for sensing signals derived from living systems. FAU - Demelas, Monia AU - Demelas M AD - Dept. of Electrical and Electronic Engineering, University of Cagliari, Piazza d'Armi, Cagliari, 09123, Italy. annalisa@diee.unica.it. FAU - Lai, Stefano AU - Lai S FAU - Spanu, Andrea AU - Spanu A FAU - Martinoia, Sergio AU - Martinoia S FAU - Cosseddu, Piero AU - Cosseddu P FAU - Barbaro, Massimo AU - Barbaro M FAU - Bonfiglio, Annalisa AU - Bonfiglio A LA - eng PT - Journal Article DEP - 20130517 PL - England TA - J Mater Chem B JT - Journal of materials chemistry. B JID - 101598493 SB - IM EDAT- 2013/08/21 00:00 MHDA- 2013/08/21 00:01 CRDT- 2020/04/09 06:00 PHST- 2020/04/09 06:00 [entrez] PHST- 2013/08/21 00:00 [pubmed] PHST- 2013/08/21 00:01 [medline] AID - 10.1039/c3tb20237b [doi] PST - ppublish SO - J Mater Chem B. 2013 Aug 21;1(31):3811-3819. doi: 10.1039/c3tb20237b. Epub 2013 May 17.