PMID- 32262410 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200408 IS - 2050-7518 (Electronic) IS - 2050-750X (Linking) VI - 3 IP - 14 DP - 2015 Apr 14 TI - Titania as a driving agent for DHICA polymerization: a novel strategy for the design of bioinspired antimicrobial nanomaterials. PG - 2808-2815 LID - 10.1039/c5tb00039d [doi] AB - Organic materials are widely employed to tune surface chemistry and/or as structuring agents of inorganic materials. Here, we propose a novel synthesis approach whereby TiO(2) not only promotes 5,6-dihydroxyindole-2-carboxylic acid (DHICA) polymerization but also acts as a templating agent for the formation itself. Hybrid TiO(2)-DHICA melanin nanostructures have been produced, showing biocide activity even under visible light conditions (activation). Hybrid nanostructures have been analyzed and characterized by multiple techniques, proving that both organic and inorganic phases strongly affect each other during in situ formation, as far as it concerns both morphology and microstructure, conferring unique biocide properties to the resulting nanomaterials. This strategy ensures much more far-reaching implementation in the synthesis of hybrid nanosystems, opening new perspectives in the design of multifunctional materials. FAU - Vitiello, Giuseppe AU - Vitiello G AD - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, Universita di Napoli "Federico II", p.le V. Tecchio 80, 80125 Napoli, Italy. giuseppina.luciani@unina.it. FAU - Pezzella, Alessandro AU - Pezzella A FAU - Zanfardino, Anna AU - Zanfardino A FAU - Varcamonti, Mario AU - Varcamonti M FAU - Silvestri, Brigida AU - Silvestri B FAU - Costantini, Aniello AU - Costantini A FAU - Branda, Francesco AU - Branda F FAU - Luciani, Giuseppina AU - Luciani G LA - eng PT - Journal Article DEP - 20150302 PL - England TA - J Mater Chem B JT - Journal of materials chemistry. B JID - 101598493 SB - IM EDAT- 2015/04/14 00:00 MHDA- 2015/04/14 00:01 CRDT- 2020/04/09 06:00 PHST- 2020/04/09 06:00 [entrez] PHST- 2015/04/14 00:00 [pubmed] PHST- 2015/04/14 00:01 [medline] AID - 10.1039/c5tb00039d [doi] PST - ppublish SO - J Mater Chem B. 2015 Apr 14;3(14):2808-2815. doi: 10.1039/c5tb00039d. Epub 2015 Mar 2.