PMID- 32263796
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200408
IS  - 2050-7518 (Electronic)
IS  - 2050-750X (Linking)
VI  - 2
IP  - 23
DP  - 2014 Jun 21
TI  - Enhancing surface characteristics of Ti-6Al-4V for bio-implants using integrated 
      anodization and thermal oxidation.
PG  - 3597-3608
LID - 10.1039/c3tb21731k [doi]
AB  - Modifications of Ti-6Al-4V surface roughness, wettability and composition are 
      increasingly studied to improve cellular viability on biomedical implants 
      involving Ti-6Al-4V. In this study, it is shown that modification of Ti-6Al-4V 
      samples using anodization (for the formation of titania nanotubes) combined with 
      thermal oxidation (TO) results in superior surface characteristics to those of a 
      smooth, rough, anodized-smooth or anodized-rough surface alone. Surface 
      characterization is performed using water contact angle (WCA) measurements, 
      white-light interferometry, Fourier transform infrared spectroscopy (FTIRS), 
      field emission scanning electron microscopy and grazing incidence X-ray 
      diffraction (GIXRD). WCA measurements before TO indicate that anodized-smooth and 
      anodized-rough samples are super-hydrophilic (WCA less than 5 degrees ); WCA of 
      non-anodized smooth and rough surfaces are 57 +/- 6 degrees  and 86 +/- 7 degrees , respectively. 
      After TO at 450  degrees C for 3 hours, all samples become super-hydrophilic; however, 
      three weeks after TO, smooth and rough surfaces become hydrophobic, while 
      anodized-smooth and anodized-rough surfaces remain hydrophilic. FTIRS and GIXRD 
      data show that the TO of anodized and non-anodized smooth samples results in 
      anatase and rutile TiO(2), of which anatase is favorable for cellular attachment. 
      Micro-/nano-scale roughness and TO are discussed in the context of enhanced 
      Ti-6Al-4V surface characteristics for improved cellular response.
FAU - Patel, Sweetu B
AU  - Patel SB
AD  - Department of Bioengineering, University of Illinois at Chicago, Chicago, 
      Illinois 60607, USA. takoudis@uic.edu.
FAU - Hamlekhan, Azhang
AU  - Hamlekhan A
FAU - Royhman, Dmitry
AU  - Royhman D
FAU - Butt, Arman
AU  - Butt A
FAU - Yuan, Judy
AU  - Yuan J
FAU - Shokuhfar, Tolou
AU  - Shokuhfar T
FAU - Sukotjo, Cortino
AU  - Sukotjo C
FAU - Mathew, Mathew T
AU  - Mathew MT
FAU - Jursich, Gregory
AU  - Jursich G
FAU - Takoudis, Christos G
AU  - Takoudis CG
LA  - eng
PT  - Journal Article
DEP - 20140507
PL  - England
TA  - J Mater Chem B
JT  - Journal of materials chemistry. B
JID - 101598493
SB  - IM
EDAT- 2014/06/21 00:00
MHDA- 2014/06/21 00:01
CRDT- 2020/04/09 06:00
PHST- 2020/04/09 06:00 [entrez]
PHST- 2014/06/21 00:00 [pubmed]
PHST- 2014/06/21 00:01 [medline]
AID - 10.1039/c3tb21731k [doi]
PST - ppublish
SO  - J Mater Chem B. 2014 Jun 21;2(23):3597-3608. doi: 10.1039/c3tb21731k. Epub 2014 
      May 7.