PMID- 32264061
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200408
IS  - 2050-7518 (Electronic)
IS  - 2050-750X (Linking)
VI  - 5
IP  - 20
DP  - 2017 May 28
TI  - Control of cell proliferation in E-jet 3D-printed scaffolds for tissue 
      engineering applications: the influence of the cell alignment angle.
PG  - 3728-3738
LID - 10.1039/c7tb00377c [doi]
AB  - The ideal 3D scaffold for biological applications has not yet been designed. Our 
      aim is to better match the scaffold performance through fine control of the 
      fabrication process. Here, we applied electro-hydrodynamic jet (E-jet) 3D 
      printing technology using poly-(lactic-co-glycolic acid) (PLGA) solution to 
      construct scaffolds for tissue engineering applications. We fabricated different 
      scaffolds of 1 : 1, 1 : 2 and 1 : 3 aspect ratios and tested the biological 
      compatibility of the 2D and 3D printed scaffolds with fibroblasts. The scaffolds 
      were used to culture fibroblasts, the main cellular components of loose 
      connective tissue. The results show that the E-jet printed scaffolds could guide 
      and improve cell growth. These scaffolds were able to support cellular alignment 
      and proliferation. The cell angle was consistent with the longitudinal direction 
      of the scaffolds, potentially enhancing the wound healing performance. Thus, the 
      potential of this flexible technology for the 3D printing of scaffolds for the 
      engineering of tissues is extensive.
FAU - Liu, Tong
AU  - Liu T
AD  - State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Biology, 
      Hunan University, Changsha, Hunan 410082, China. tanzk@hnu.edu.cn.
FAU - Huang, Ruiying
AU  - Huang R
FAU - Zhong, Juchang
AU  - Zhong J
FAU - Yang, Yikun
AU  - Yang Y
FAU - Tan, Zhikai
AU  - Tan Z
FAU - Tan, Weihong
AU  - Tan W
LA  - eng
PT  - Journal Article
DEP - 20170502
PL  - England
TA  - J Mater Chem B
JT  - Journal of materials chemistry. B
JID - 101598493
SB  - IM
EDAT- 2017/05/28 00:00
MHDA- 2017/05/28 00:01
CRDT- 2020/04/09 06:00
PHST- 2020/04/09 06:00 [entrez]
PHST- 2017/05/28 00:00 [pubmed]
PHST- 2017/05/28 00:01 [medline]
AID - 10.1039/c7tb00377c [doi]
PST - ppublish
SO  - J Mater Chem B. 2017 May 28;5(20):3728-3738. doi: 10.1039/c7tb00377c. Epub 2017 
      May 2.