PMID- 32264295 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200408 IS - 2050-7518 (Electronic) IS - 2050-750X (Linking) VI - 5 IP - 19 DP - 2017 May 21 TI - Highly selective organic transistor biosensor with inkjet printed graphene oxide support system. PG - 3580-3585 LID - 10.1039/c6tb03357a [doi] AB - Most of the reported field effect transistors (FETs) fall short of a general method to uniquely specify and detect a target analyte. For this reason, we propose a pentacene-based FET with a graphene oxide support system (GOSS), composed of functionalized graphene oxide (GO) ink. The GOSS with a specific moiety group to capture the biomaterial of interest was inkjet printed on the pentacene FET. It provided modular receptor sites on the surface of pentacene, without alteration of the device. To evaluate the performance of a GOSS-pentacene FET biosensor, we detected the artificial DNA and circulating tumor cells as a proof-of-concept. The mobility of the FET dramatically changed upon capturing the target biomolecule on the GOSS. The FET exhibited high selectivity with 0.1 pmoles of the target DNA and a few cancer cells per detection volume. This study suggests a valuable sensor for medical diagnosis that can be mass produced effortlessly at low-cost. FAU - Lee, Dong-Hoon AU - Lee DH AD - School of Electronic and Electrical Engineering, Sungkyunkwan University, Suwon, Gyeonggi 16419, South Korea. yongsang@skku.edu. FAU - Cho, Hee-Sang AU - Cho HS FAU - Han, Dawoon AU - Han D FAU - Chand, Rohit AU - Chand R FAU - Yoon, Tae-Jong AU - Yoon TJ FAU - Kim, Yong-Sang AU - Kim YS LA - eng PT - Journal Article DEP - 20170426 PL - England TA - J Mater Chem B JT - Journal of materials chemistry. B JID - 101598493 SB - IM EDAT- 2017/05/21 00:00 MHDA- 2017/05/21 00:01 CRDT- 2020/04/09 06:00 PHST- 2020/04/09 06:00 [entrez] PHST- 2017/05/21 00:00 [pubmed] PHST- 2017/05/21 00:01 [medline] AID - 10.1039/c6tb03357a [doi] PST - ppublish SO - J Mater Chem B. 2017 May 21;5(19):3580-3585. doi: 10.1039/c6tb03357a. Epub 2017 Apr 26.