PMID- 32267721
OWN - NLM
STAT- MEDLINE
DCOM- 20200629
LR  - 20220415
IS  - 1748-880X (Electronic)
IS  - 0007-1285 (Print)
IS  - 0007-1285 (Linking)
VI  - 93
IP  - 1111
DP  - 2020 Jul
TI  - A UK wide study of current prostate planning practice.
PG  - 20200142
LID - 10.1259/bjr.20200142 [doi]
LID - 20200142
AB  - OBJECTIVES: The objective of this work was to undertake a non-judgemental study 
      of prostate planning practice across the UK by inviting all departments to 
      undertake the same case. METHODS: An invitation to take part in the study was 
      sent to the Heads of all UK radiotherapy departments and posted on the UK Medical 
      Physics mailbase. Individuals interested in participating were able to access a 
      single anonymised CT dataset for download with the prostate gland, seminal 
      vesicles, bladder, rectum, bowel, femoral heads, and penile bulb outlined. A 
      brief patient history was also supplied. Participants were asked to create 
      planning target volumes (PTVs) according to their local clinical protocol and 
      plan to give 60 Gy in 20 fractions to the PTV receiving the highest dose. No 
      guidance was given for acceptable organ at risk doses. Dicom plan and dose 
      information was loaded back into ProKnow for analysis by contributors. RESULTS: 
      There were 102 plan submissions made to the study representing 48 different UK 
      radiotherapy departments. Seventeen distinct methodologies for creating the 
      prescription PTV from the prostate and seminal vesicles were identified with the 
      ethos of the CHHIP trial protocol for margin growing followed in nearly 
      two-thirds of cases. Positive correlations were found when assessing the doses 
      received by the bladder and rectum against the volume of the PTV to which 60 Gy 
      was prescribed. CONCLUSIONS: A national planning study whereby staff from a 
      multitude of radiotherapy departments create plans based solely on a single 
      dataset is feasible. The cohort of data was made available to all participants 
      following the study to enable self-assessment and benchmarking against that of 
      their peers. ADVANCES IN KNOWLEDGE: This is the first UK wide treatment planning 
      study to investigate local clinical prostate planning practice. This has given UK 
      departments the opportunity to evaluate their planning practices against those of 
      their peers.
FAU - Taylor, Timothy
AU  - Taylor T
AD  - Department of Medical Physics & Bioengineering, Royal United Hospitals Bath NHS 
      Foundation Trust, Combe Park, Bath, BA1 3NG.
FAU - Richmond, Neil
AU  - Richmond N
AD  - Northern Centre for Cancer Care, Freeman Hospital, Freeman Road, Newcastle upon 
      Tyne, NE7 7DN.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20200424
PL  - England
TA  - Br J Radiol
JT  - The British journal of radiology
JID - 0373125
SB  - IM
MH  - Humans
MH  - Male
MH  - *Patient Care Planning
MH  - Practice Patterns, Physicians'/statistics & numerical data
MH  - Prostate/radiation effects
MH  - Prostatic Neoplasms/*radiotherapy
MH  - Radiation Dosage
MH  - Radiology Department, Hospital
MH  - Radiotherapy Dosage
MH  - Rectum/radiation effects
MH  - Retrospective Studies
MH  - Surveys and Questionnaires
MH  - United Kingdom
MH  - Urethra/radiation effects
MH  - Urinary Bladder/radiation effects
PMC - PMC7336059
EDAT- 2020/04/09 06:00
MHDA- 2020/07/01 06:00
PMCR- 2021/07/01
CRDT- 2020/04/09 06:00
PHST- 2020/04/09 06:00 [pubmed]
PHST- 2020/07/01 06:00 [medline]
PHST- 2020/04/09 06:00 [entrez]
PHST- 2021/07/01 00:00 [pmc-release]
AID - 10.1259/bjr.20200142 [doi]
PST - ppublish
SO  - Br J Radiol. 2020 Jul;93(1111):20200142. doi: 10.1259/bjr.20200142. Epub 2020 Apr 
      24.