PMID- 32269777
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240328
IS  - 2051-3380 (Print)
IS  - 2051-3380 (Electronic)
IS  - 2051-3380 (Linking)
VI  - 8
IP  - 4
DP  - 2020 May
TI  - Relapse of cervical tuberculous lymphadenitis immediately after completion of 
      effective anti-tuberculosis treatments.
PG  - e00555
LID - 10.1002/rcr2.555 [doi]
LID - e00555
AB  - Most cases of lymph node enlargement after completing tuberculosis (TB) treatment 
      are due to paradoxical reaction (PR), not relapse, and therefore, do not require 
      re-treatment. We herein report a case of a 28-year-old man who had developed 
      cervical TB lymphadenitis and exhibited re-enlargement of the same lymph nodes 
      one month after completing effective TB chemotherapy, which was microbiologically 
      proven as relapse. The patient noticed painful cervical lymphadenopathy one month 
      after completion of chemotherapy for TB lymphadenitis. Combination chemotherapy 
      with multiple anti-TB drugs was resumed with suspicion of relapse. But, with his 
      symptoms having worsened, surgical excision was performed. Mycobacterium 
      tuberculosis was cultured from the dissected lymph nodes. Early regrowth of the 
      lymph nodes after completing treatment can derive from microbiological relapse, 
      in addition to PR. Surgical excision was useful for the microbiological diagnosis 
      of the relapse. We must take care of lymph node re-enlargement in consideration 
      of TB relapse.
CI  - (c) 2020 The Authors. Respirology Case Reports published by John Wiley & Sons 
      Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
FAU - Kimura, Yuya
AU  - Kimura Y
AUID- ORCID: 0000-0003-1649-0596
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
FAU - Shimada, Masahiro
AU  - Shimada M
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
FAU - Kawashima, Masahiro
AU  - Kawashima M
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
FAU - Yamane, Akira
AU  - Yamane A
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
FAU - Nagai, Hideaki
AU  - Nagai H
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
FAU - Matsui, Hirotoshi
AU  - Matsui H
AD  - Center for Pulmonary Diseases National Hospital Organization Tokyo National 
      Hospital Tokyo Japan.
LA  - eng
PT  - Case Reports
DEP - 20200407
PL  - United States
TA  - Respirol Case Rep
JT  - Respirology case reports
JID - 101631052
PMC - PMC7136954
OTO - NOTNLM
OT  - Cervical tuberculous lymphadenitis
OT  - paradoxical reaction
OT  - relapse
OT  - surgical excision
EDAT- 2020/04/10 06:00
MHDA- 2020/04/10 06:01
PMCR- 2020/04/07
CRDT- 2020/04/10 06:00
PHST- 2020/03/03 00:00 [received]
PHST- 2020/03/12 00:00 [revised]
PHST- 2020/03/19 00:00 [accepted]
PHST- 2020/04/10 06:00 [entrez]
PHST- 2020/04/10 06:00 [pubmed]
PHST- 2020/04/10 06:01 [medline]
PHST- 2020/04/07 00:00 [pmc-release]
AID - RCR2555 [pii]
AID - 10.1002/rcr2.555 [doi]
PST - epublish
SO  - Respirol Case Rep. 2020 Apr 7;8(4):e00555. doi: 10.1002/rcr2.555. eCollection 
      2020 May.