PMID- 32270185
OWN - NLM
STAT- MEDLINE
DCOM- 20210222
LR  - 20210410
IS  - 1758-535X (Electronic)
IS  - 1079-5006 (Print)
IS  - 1079-5006 (Linking)
VI  - 75
IP  - 12
DP  - 2020 Nov 13
TI  - Association Between Improved Mobility and Distal Health Outcomes.
PG  - 2412-2417
LID - 10.1093/gerona/glaa086 [doi]
AB  - BACKGROUND: We examined the association between improved mobility and distal 
      health outcomes in older adults using secondary analysis of data from a 
      cluster-randomized controlled group exercise trial. METHODS: Participants were 
      303 men and women aged >/=65 and older in 32 independent living facilities, senior 
      apartments, and community centers who participated in 12-week group exercise 
      interventions. Included were those who completed >/=1 follow-up phone call 
      regarding outcomes assessment in the following year. Gait speed and 6-minute walk 
      distance (6MWD) were assessed at baseline and immediately after 12-week 
      interventions to determine mobility performance change status. Falls, emergency 
      department (ED) visits, and hospitalizations were assessed monthly for 12 months 
      following the end of interventions via interactive voice response phone calls. 
      Incident rate ratios (IRRs) were calculated to quantify incidence of adverse 
      outcomes with respect to mobility performance change. RESULTS: Each 0.05 m/s 
      increase in gait speed resulted in an 11% reduction in falls (IRR = 0.89; 95% 
      confidence interval [CI], 0.84-0.94; p < .0001); a similar decrease was seen for 
      each 20 m increase in 6MWD (IRR = 0.89; 95% CI, 0.83-0.93; p = .0003). Those who 
      improved gait speed had 61 falls per 1,000 person-months versus 135 in those who 
      had no change/a decline. Those who improved 6MWD had 67 falls per 1,000 
      person-months versus 110 per 1,000 person-months in those who had no change/a 
      decline. Differences in ED visits and hospitalizations were not statistically 
      significant. CONCLUSION: Improvements in mobility performance are associated with 
      lower incidence of future falls. Given the exploratory nature of the findings, 
      further investigation is warranted.
CI  - (c) The Author(s) 2020. Published by Oxford University Press on behalf of The 
      Gerontological Society of America. All rights reserved. For permissions, please 
      e-mail: journals.permissions@oup.com.
FAU - Shuman, Valerie
AU  - Shuman V
AD  - Department of Physical Therapy, University of Pittsburgh, Pennsylvania.
FAU - Coyle, Peter C
AU  - Coyle PC
AD  - Department of Physical Therapy, University of Delaware, Newark.
FAU - Perera, Subashan
AU  - Perera S
AD  - Department of Medicine, University of Pittsburgh, Pennsylvania.
AD  - Department of Biostatistics, University of Pittsburgh, Pennsylvania.
FAU - Van Swearingen, Jessie M
AU  - Van Swearingen JM
AD  - Department of Physical Therapy, University of Pittsburgh, Pennsylvania.
FAU - Albert, Steve M
AU  - Albert SM
AD  - Department of Behavioral and Community Health Sciences, University of Pittsburgh, 
      Pennsylvania.
FAU - Brach, Jennifer S
AU  - Brach JS
AD  - Department of Physical Therapy, University of Pittsburgh, Pennsylvania.
LA  - eng
GR  - K24 AG057728/AG/NIA NIH HHS/United States
GR  - P30 AG024827/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Gerontol A Biol Sci Med Sci
JT  - The journals of gerontology. Series A, Biological sciences and medical sciences
JID - 9502837
SB  - IM
MH  - Accidental Falls/*prevention & control/*statistics & numerical data
MH  - Aged
MH  - Aged, 80 and over
MH  - Emergency Service, Hospital/statistics & numerical data
MH  - *Exercise Therapy
MH  - Female
MH  - Group Processes
MH  - Hospitalization/statistics & numerical data
MH  - Humans
MH  - Incidence
MH  - Male
MH  - *Mobility Limitation
MH  - Telephone
MH  - Walk Test
MH  - Walking Speed
PMC - PMC7662180
OTO - NOTNLM
OT  - Falls
OT  - Gait
OT  - Outcomes
OT  - Physical activity
EDAT- 2020/04/10 06:00
MHDA- 2021/02/23 06:00
PMCR- 2021/04/09
CRDT- 2020/04/10 06:00
PHST- 2019/10/11 00:00 [received]
PHST- 2020/04/10 06:00 [pubmed]
PHST- 2021/02/23 06:00 [medline]
PHST- 2020/04/10 06:00 [entrez]
PHST- 2021/04/09 00:00 [pmc-release]
AID - 5818089 [pii]
AID - glaa086 [pii]
AID - 10.1093/gerona/glaa086 [doi]
PST - ppublish
SO  - J Gerontol A Biol Sci Med Sci. 2020 Nov 13;75(12):2412-2417. doi: 
      10.1093/gerona/glaa086.