PMID- 32273185
OWN - NLM
STAT- MEDLINE
DCOM- 20210317
LR  - 20210317
IS  - 1873-2518 (Electronic)
IS  - 0264-410X (Linking)
VI  - 38
IP  - 21
DP  - 2020 May 6
TI  - Age inappropriate influenza vaccination in infants less than 6 months old, 
      2010-2018.
PG  - 3747-3751
LID - S0264-410X(20)30418-7 [pii]
LID - 10.1016/j.vaccine.2020.03.039 [doi]
AB  - BACKGROUND: Annual influenza vaccination is recommended for persons 6 months or 
      older and vaccination in infants less than 6 months old is a vaccine 
      administration error. There are limited safety studies in this population, 
      particularly among infants less than 6 weeks old. METHODS: We searched the U.S. 
      Vaccine Adverse Event Reporting System (VAERS) database for reports of adverse 
      events (AEs) following influenza vaccination in infants less than 6 months old 
      for the 2010-2018 influenza seasons. We conducted a descriptive and qualitative 
      analysis of reports to describe AEs and identify possible risk factors. RESULTS: 
      In total, 114 reports were identified; only 21 reported a specific AE. Pyrexia, 
      irritability, crying and diarrhea were the most common symptoms. There were 12 
      reports involving newborns; the most common circumstance cited was confusion with 
      the birth dose of hepatitis B vaccine. The following risk factors were 
      identified: (1) individuals getting vaccinated together resulting in patient 
      mix-ups; (2) healthcare provider not verifying the patient's information; (3) 
      individual provider confusion due to similarities in vaccines' packaging and 
      names of vaccines that sound alike. CONCLUSIONS: Reports identified of influenza 
      vaccination in infants less than 6 months old indicate that vaccination errors in 
      this age group are occurring and healthcare providers who vaccinate infants 
      should be aware of how to prevent such events. Our study adds to the existing 
      literature by providing valuable information regarding the general absence of 
      serious adverse events in the case of vaccination errors associated with 
      inadvertent influenza vaccine within this population.
CI  - Published by Elsevier Ltd.
FAU - Suragh, Tiffany A
AU  - Suragh TA
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion, National 
      Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control 
      and Prevention, United States. Electronic address: Tsuragh@cdc.gov.
FAU - Hibbs, Beth
AU  - Hibbs B
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion, National 
      Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control 
      and Prevention, United States.
FAU - Marquez, Paige
AU  - Marquez P
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion, National 
      Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control 
      and Prevention, United States.
FAU - McNeil, Michael M
AU  - McNeil MM
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion, National 
      Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control 
      and Prevention, United States.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200406
PL  - Netherlands
TA  - Vaccine
JT  - Vaccine
JID - 8406899
RN  - 0 (Hepatitis B Vaccines)
RN  - 0 (Influenza Vaccines)
SB  - IM
MH  - Adverse Drug Reaction Reporting Systems
MH  - Age Factors
MH  - Hepatitis B Vaccines
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - *Influenza Vaccines/adverse effects
MH  - *Influenza, Human/prevention & control
MH  - Medical Errors
MH  - Vaccination/adverse effects
OTO - NOTNLM
OT  - Immunization
OT  - Influenza vaccine
OT  - Medical errors
OT  - Vaccination errors
OT  - Vaccine Adverse Event Reporting System (VAERS)
OT  - Vaccine safety
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/04/11 06:00
MHDA- 2021/03/18 06:00
CRDT- 2020/04/11 06:00
PHST- 2019/12/23 00:00 [received]
PHST- 2020/03/19 00:00 [revised]
PHST- 2020/03/22 00:00 [accepted]
PHST- 2020/04/11 06:00 [pubmed]
PHST- 2021/03/18 06:00 [medline]
PHST- 2020/04/11 06:00 [entrez]
AID - S0264-410X(20)30418-7 [pii]
AID - 10.1016/j.vaccine.2020.03.039 [doi]
PST - ppublish
SO  - Vaccine. 2020 May 6;38(21):3747-3751. doi: 10.1016/j.vaccine.2020.03.039. Epub 
      2020 Apr 6.