PMID- 32276841
OWN - NLM
STAT- MEDLINE
DCOM- 20201224
LR  - 20201224
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 52
IP  - 8
DP  - 2020 Oct
TI  - Pure Red Cell Aplasia and Antibody-Mediated Rejection: Double Trouble in 1 Kidney 
      Transplant Recipient Solved by Intravenous Immunoglobulin Infusion: A Case 
      Report.
PG  - 2530-2532
LID - S0041-1345(19)31279-5 [pii]
LID - 10.1016/j.transproceed.2020.01.091 [doi]
AB  - Acquired pure red cell aplasia (PRCA) is characterized by severe normocytic 
      (rarely macrocytic) and normochromic anemia, a low reticulocytes count in 
      peripheral blood, and near absence of erythroid precursors in the bone marrow, 
      with a normal level of erythropoietin. We describe a case of the kidney 
      transplant recipient, diagnosed with PRCA induced with parvovirus B19 infection. 
      Our case demonstrates that although this complication is rare, it should be 
      considered in a differential diagnosis of anemia diagnostics in immunocompromised 
      patients. In our case reduced immune response resulted from post-transplant 
      immunosuppressive therapy. In our patient, apart from infection by parvovirus 
      B19, graft dysfunction due to polyomavirus BK virus infection was also detected 
      together with histologic and serologic features of antibody-mediated renal graft 
      rejection. Considering the entire clinical picture, intravenous immunoglobulin 
      therapy (IVIg) was successfully introduced.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Knysak, Monika
AU  - Knysak M
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland. 
      Electronic address: makb@poczta.fm.
FAU - Napora, Maria
AU  - Napora M
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
FAU - Misiukiewicz-Poc, Magdalena
AU  - Misiukiewicz-Poc M
AD  - Department of Patomorphology, University of Warmia and Mazury in Olsztyn, 
      Olsztyn, Poland.
FAU - Pawlowska, Anna
AU  - Pawlowska A
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
FAU - Kwella, Norbert
AU  - Kwella N
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
FAU - Zbrzezniak, Justyna
AU  - Zbrzezniak J
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
FAU - Winiarska, Agata
AU  - Winiarska A
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
FAU - Stompor, Tomasz
AU  - Stompor T
AD  - Department of Internal Medicine, Clinic of Nephrology, Hypertension and Internal 
      Diseases of the University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200408
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (Antibodies, Viral)
RN  - 0 (EPO protein, human)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 11096-26-7 (Erythropoietin)
SB  - IM
MH  - Antibodies, Viral/immunology
MH  - Erythema Infectiosum/immunology/virology
MH  - Erythropoietin
MH  - Female
MH  - Graft Rejection/drug therapy/*immunology/virology
MH  - Humans
MH  - Immunocompromised Host/*immunology
MH  - Immunoglobulins, Intravenous/administration & dosage
MH  - Kidney Transplantation/*adverse effects
MH  - Male
MH  - Middle Aged
MH  - Parvovirus B19, Human/immunology
MH  - Postoperative Complications/drug therapy/*immunology/virology
MH  - Red-Cell Aplasia, Pure/drug therapy/*immunology/*virology
EDAT- 2020/04/12 06:00
MHDA- 2020/12/29 06:00
CRDT- 2020/04/12 06:00
PHST- 2019/11/27 00:00 [received]
PHST- 2020/01/02 00:00 [accepted]
PHST- 2020/04/12 06:00 [pubmed]
PHST- 2020/12/29 06:00 [medline]
PHST- 2020/04/12 06:00 [entrez]
AID - S0041-1345(19)31279-5 [pii]
AID - 10.1016/j.transproceed.2020.01.091 [doi]
PST - ppublish
SO  - Transplant Proc. 2020 Oct;52(8):2530-2532. doi: 
      10.1016/j.transproceed.2020.01.091. Epub 2020 Apr 8.