PMID- 32279842 OWN - NLM STAT- MEDLINE DCOM- 20200828 LR - 20200828 IS - 1879-1913 (Electronic) IS - 0002-9149 (Linking) VI - 125 IP - 11 DP - 2020 Jun 1 TI - Regional Variation in Procedural and Clinical Outcomes Among Patients With ST Elevation Myocardial Infarction With Cardiogenic Shock. PG - 1612-1618 LID - S0002-9149(20)30207-1 [pii] LID - 10.1016/j.amjcard.2020.02.033 [doi] AB - There is limited data on regional differences in patient characteristics, practice patterns, and clinical outcomes in patients with ST elevation myocardial infarction (STEMI) with cardiogenic shock (CS) in the United States (US). We aimed to identify variations in treatment methods and clinical outcomes in patients with STEMI CS between the 4 US regions. Using the National Inpatient Sample database, we identified adult patients admitted with STEMI associated with CS between 2006 and 2015 using ICD-9-DM codes. Based on the US regions (Northeast, Midwest, South, and West), we divided patients in 4 cohorts and compared baseline patient characteristics, clinical outcomes and procedural outcomes. A total of 186,316 patients with STEMI CS were included; 32,303 (17.3%) were hospitalized in the Northeast, 43,634 (23.4%) in the Midwest, 70,036 (37.8%) in the South, and 40,043 (21.5%) in the West. Although nonstatistically significant, the in-hospital mortality was higher in Northeast region (37.7%), followed by the South (36.6%), West (35.7%), and Midwest (35.2%). Rates of percutaneous coronary intervention were higher in the Midwest (68.5%) and lower in the Northeast (56%). The use of percutaneous ventricular assist device and ECMO was higher in the Northeast (3.3% and 2.2%) and lower in the West (2.1% and 0.4%). The median length of stay was similar among all 4 cohorts (6 days) but median hospital costs were higher in the West ($36, 614) and lower in the South ($28,795). In conclusion, there are significant geographic variations in practice patterns, healthcare cost, and in-hospital outcomes in patients with STEMI complicated by CS between 4 US regions. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Lemor, Alejandro AU - Lemor A AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan; Centro de Investigacion de Epidemiologia Clinica y Medicina Basada en la Evidencia, Facultad de Medicina, Universidad de San Martin de Porres, Lima, Peru. Electronic address: alejandrolemor@outlook.com. FAU - Gorgis, Sarah AU - Gorgis S AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. FAU - Villablanca, Pedro A AU - Villablanca PA AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. FAU - Basir, Mir B AU - Basir MB AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. FAU - Voeltz, Michele AU - Voeltz M AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. FAU - Alaswad, Khaldoon AU - Alaswad K AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. FAU - O'Neill, William AU - O'Neill W AD - Division of Cardiology, Henry Ford Hospital, Detroit, Michigan. LA - eng PT - Journal Article DEP - 20200316 PL - United States TA - Am J Cardiol JT - The American journal of cardiology JID - 0207277 SB - IM MH - Aged MH - Cardiac Catheterization/*statistics & numerical data MH - Cohort Studies MH - Comorbidity MH - Coronary Artery Bypass/*statistics & numerical data MH - Extracorporeal Membrane Oxygenation/*statistics & numerical data MH - Female MH - Geography MH - Health Care Costs/statistics & numerical data MH - Heart-Assist Devices/*statistics & numerical data MH - Hospital Costs/statistics & numerical data MH - Hospital Mortality MH - Humans MH - Intra-Aortic Balloon Pumping/*statistics & numerical data MH - Male MH - Percutaneous Coronary Intervention/*statistics & numerical data MH - Prognosis MH - ST Elevation Myocardial Infarction/complications/economics/mortality/*therapy MH - Shock, Cardiogenic/economics/etiology/mortality/*therapy MH - United States/epidemiology EDAT- 2020/04/14 06:00 MHDA- 2020/08/29 06:00 CRDT- 2020/04/14 06:00 PHST- 2020/01/08 00:00 [received] PHST- 2020/02/23 00:00 [revised] PHST- 2020/02/27 00:00 [accepted] PHST- 2020/04/14 06:00 [pubmed] PHST- 2020/08/29 06:00 [medline] PHST- 2020/04/14 06:00 [entrez] AID - S0002-9149(20)30207-1 [pii] AID - 10.1016/j.amjcard.2020.02.033 [doi] PST - ppublish SO - Am J Cardiol. 2020 Jun 1;125(11):1612-1618. doi: 10.1016/j.amjcard.2020.02.033. Epub 2020 Mar 16.