PMID- 32280252
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220413
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 13
DP  - 2020
TI  - Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic 
      Patients: A Retrospective Analysis.
PG  - 935-941
LID - 10.2147/DMSO.S235546 [doi]
AB  - PURPOSE: To find out the association of dyslipidemia and comorbidities with risk 
      factors among type-2 diabetes mellitus (T2DM) patients attending King Abdulaziz 
      University Hospital (KAUH) Jeddah, Saudi Arabia (SA). PATIENTS AND METHODS: Three 
      hundred and twenty-five T2DM patients were enrolled from the electronic record of 
      the KAUH. The patients' existing comorbidities and dyslipidemia correlation with 
      demographic, clinical, and available laboratory data were sought. Statistical 
      analysis was performed on SPSS-23. RESULTS: Of the total 325 T2DM patients with a 
      mean age of 60.13+/-10.5 years [males 95 (29.23%) and females 230 (70.77%)] were 
      included from the electronic record. Poor glycemic control was observed in 222 
      (68.31%) subjects (HbA1c > 7%), and 154 (47.39%) subjects had DM for more than 
      ten years. Among our study subjects, 103 (31.69%) were hypertensive (HTN), 112 
      (34.46%) had ischemic heart disease (IHD), 45 (13.85%) were obese, 8(2.46%) had a 
      stroke and 269 (82.77%) had dyslipidemia. Of the total 269 dyslipidemic 
      patients,168 (62.45%) were on hypolipidemic treatment. On comparison of study 
      variables according to dyslipidemia versus normal lipid levels, the lipid 
      profile, including HDLc, LDLc, TC, and TG, revealed a highly significant 
      difference (p-value <0.001) whereas many variables were not significantly 
      different. HBA1c, FBG, and RBG were significantly higher in dyslipidemic 
      subjects. Logistic regression analysis of risk factors and comorbidities in our 
      patients revealed that age 60-69 years and 70-79 years had a significant 
      association with comorbidities. Similarly, logistic regression analysis of risk 
      factors and dyslipidemia in our patients revealed no statistically significant 
      association. CONCLUSION: Our results observed that the comorbidities were 
      associated with increasing age and common comorbidities were HTN, IHD, 
      dyslipidemia. Our study has highlighted the current trends in T2DM symptomatology 
      and comorbidities. Efficient management and control by early screening and 
      developing healthy lifestyles in our patients can be very helpful in the 
      prevention of all these highly morbid complications of this preventable disease.
CI  - (c) 2020 Gazzaz et al.
FAU - Gazzaz, Zohair Jamil
AU  - Gazzaz ZJ
AD  - Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz 
      University, Jeddah, Saudi Arabia.
FAU - Iftikhar, Rahila
AU  - Iftikhar R
AD  - Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
FAU - Jameel, Tahir
AU  - Jameel T
AD  - Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz 
      University, Jeddah, Saudi Arabia.
FAU - Baig, Mukhtiar
AU  - Baig M
AUID- ORCID: 0000-0003-0058-2031
AD  - Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz 
      University, Jeddah, Saudi Arabia.
FAU - Murad, Manal Abdulaziz
AU  - Murad MA
AUID- ORCID: 0000-0001-8650-6691
AD  - Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
LA  - eng
PT  - Journal Article
DEP - 20200330
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC7125330
OTO - NOTNLM
OT  - DM
OT  - HbA1c
OT  - IHD
OT  - cholesterol
OT  - comorbidities
OT  - dyslipidemia
OT  - hypertension
COIS- The authors report no conflicts of interest in this work.
EDAT- 2020/04/14 06:00
MHDA- 2020/04/14 06:01
PMCR- 2020/03/30
CRDT- 2020/04/14 06:00
PHST- 2019/10/21 00:00 [received]
PHST- 2020/03/11 00:00 [accepted]
PHST- 2020/04/14 06:00 [entrez]
PHST- 2020/04/14 06:00 [pubmed]
PHST- 2020/04/14 06:01 [medline]
PHST- 2020/03/30 00:00 [pmc-release]
AID - 235546 [pii]
AID - 10.2147/DMSO.S235546 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2020 Mar 30;13:935-941. doi: 10.2147/DMSO.S235546. 
      eCollection 2020.