PMID- 32282647
OWN - NLM
STAT- MEDLINE
DCOM- 20210914
LR  - 20210914
IS  - 1539-2864 (Electronic)
IS  - 0275-004X (Linking)
VI  - 41
IP  - 1
DP  - 2021 Jan 1
TI  - EPIDEMIOLOGY OF VITREOMACULAR INTERFACE ABNORMALITIES USING MACULAR 
      SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN AN ELDERLY POPULATION (THE 
      MONTRACHET STUDY).
PG  - 60-67
LID - 10.1097/IAE.0000000000002802 [doi]
AB  - PURPOSE: The aim of this study was to investigate the prevalence of vitreomacular 
      interface abnormalities (VMIAs) and to identify associated factors in an elderly 
      population in Europe. METHODS: The MONTRACHET (Maculopathy Optic Nerve nuTRition 
      neurovAsCular and HEarT diseases) Study is a population-based study, conducted in 
      subjects older than 75 years. Vitreomacular adhesions, vitreomacular tractions, 
      macular holes, epiretinal membranes, and macular cysts were assessed on 
      spectral-domain optical coherence tomography examinations. The prevalence of 
      VMIAs was estimated. We studied the association of demographic and clinical 
      factors with VMIAs. RESULTS: The mean age of the participants was 82.3 (SD, 3.8) 
      years, and 37.3% were men. The prevalence rates of VMIAs were vitreomacular 
      adhesions (17.7%), vitreomacular tractions (1.4%), lamellar macular holes (1.0%), 
      full-thickness macular holes (0.2%), macular pseudoholes (0.4%), epiretinal 
      membranes (38.9%), and macular cysts (5.8%). In multivariate analysis, 
      vitreomacular adhesions were positively associated with male sex (P < 0.001) and 
      negatively associated with older age (P < 0.001) and cataract extraction (P < 
      0.001). Epiretinal membranes were positively associated with older age (P < 
      0.001) and cataract extraction (P < 0.001). CONCLUSION: The prevalence of VMIAs 
      based on spectral-domain optical coherence tomography analysis was high in 
      subjects older than 75 years.
FAU - Ben Ghezala, Ines
AU  - Ben Ghezala I
AD  - Ophthalmology Department, Dijon-Bourgogne University Hospital, Dijon, France.
AD  - Clinical Epidemiology Unit, Inserm, CIC 1432, Dijon, France.
FAU - Seydou, Alassane
AU  - Seydou A
AD  - Clinical Epidemiology Unit, Inserm, CIC 1432, Dijon, France.
AD  - Clinical Epidemiology/Clinical Trials Unit, Dijon-Bourgogne University Hospital, 
      Clinical Investigation Center, Dijon, France.
FAU - Gabrielle, Pierre-Henry
AU  - Gabrielle PH
AD  - Ophthalmology Department, Dijon-Bourgogne University Hospital, Dijon, France.
AD  - Clinical Epidemiology/Clinical Trials Unit, Dijon-Bourgogne University Hospital, 
      Clinical Investigation Center, Dijon, France.
FAU - Bouche-Pillon, Jacques
AU  - Bouche-Pillon J
AD  - Ophthalmology Department, Dijon-Bourgogne University Hospital, Dijon, France.
FAU - Binquet, Christine
AU  - Binquet C
AD  - Clinical Epidemiology Unit, Inserm, CIC 1432, Dijon, France.
FAU - Delcourt, Cecile
AU  - Delcourt C
AD  - Eye and Nutrition Group, Centre des Sciences du Gout et de l'Alimentation, CNRS, 
      INRAe, University Bourgogne Franche-Comte, Dijon, France.
FAU - Daien, Vincent
AU  - Daien V
AD  - Bordeaux Population Health Research Center, University of Bordeaux, Inserm, Team 
      LEHA, UMR 1219, Bordeaux, France.
AD  - Department of Ophthalmology, Gui de Chauliac Hospital, Montpellier, France; and.
FAU - Bron, Alain M
AU  - Bron AM
AD  - Ophthalmology Department, Dijon-Bourgogne University Hospital, Dijon, France.
AD  - Clinical Epidemiology/Clinical Trials Unit, Dijon-Bourgogne University Hospital, 
      Clinical Investigation Center, Dijon, France.
FAU - Creuzot-Garcher, Catherine
AU  - Creuzot-Garcher C
AD  - Ophthalmology Department, Dijon-Bourgogne University Hospital, Dijon, France.
AD  - Clinical Epidemiology/Clinical Trials Unit, Dijon-Bourgogne University Hospital, 
      Clinical Investigation Center, Dijon, France.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - United States
TA  - Retina
JT  - Retina (Philadelphia, Pa.)
JID - 8309919
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - France/epidemiology
MH  - Humans
MH  - Male
MH  - *Population Surveillance
MH  - Prevalence
MH  - Retinal Diseases/diagnosis/*epidemiology
MH  - Tomography, Optical Coherence/*methods
MH  - *Visual Acuity
MH  - Vitreous Body/*pathology
EDAT- 2020/04/14 06:00
MHDA- 2021/09/15 06:00
CRDT- 2020/04/14 06:00
PHST- 2020/04/14 06:00 [pubmed]
PHST- 2021/09/15 06:00 [medline]
PHST- 2020/04/14 06:00 [entrez]
AID - 00006982-202101000-00007 [pii]
AID - 10.1097/IAE.0000000000002802 [doi]
PST - ppublish
SO  - Retina. 2021 Jan 1;41(1):60-67. doi: 10.1097/IAE.0000000000002802.