PMID- 32282775
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1536-4828 (Electronic)
IS  - 0885-3177 (Linking)
VI  - 49
IP  - 4
DP  - 2020 Apr
TI  - Acute Pancreatitis in Patients With a Medical History of Type 2 Diabetes 
      Mellitus: Clinical Findings and Magnetic Resonance Imaging Characteristics.
PG  - 591-597
LID - 10.1097/MPA.0000000000001530 [doi]
AB  - OBJECTIVE: To determine the characteristics of type 2 diabetes mellitus 
      (T2DM)-related acute pancreatitis (AP) on magnetic resonance imaging (MRI). 
      METHODS: Retrospectively studied 262 patients with AP were admitted to our 
      institution and underwent MRI. Diagnosis of T2DM-related AP was based on clinical 
      manifestations, laboratory tests, and MRI. Pancreatic/peripancreatic changes were 
      assessed on MRI. RESULTS: Fifty-three (20.2%) patients with T2DM-related AP and 
      209 (79.8%) with nondiabetic AP were enrolled. On MRI, a higher prevalence of 
      necrotizing pancreatitis (P < 0.001), pancreatic necrosis >30% (57.5% vs 29.2%; P 
      = 0.006), hemorrhage (35.8% vs 19.1%; P = 0.009), abdominal wall edema (67.9% vs 
      46.8%; P = 0.006), walled-off necrosis (43.2% vs 14.6%; P < 0.001), and infected 
      collections (P < 0.001) were registered in T2DM with AP. T2DM-related AP 
      sustained greater magnetic resonance severity index (mean, 5.1 [range, 2-10] vs 
      3.4 [range, 1-10]; P < 0.001), higher incidence of moderate and severe 
      pancreatitis (69.8% vs 40.2%; P < 0.001), higher organ failure (45.3% vs 22%; P = 
      0.001), and prolonged hospitalization (mean, 25.2 [range, 10-63] vs 16 [range, 
      5-48] days; P < 0.001). CONCLUSIONS: Type 2 diabetes mellitus-related AP is more 
      moderate-to-severe pancreatitis, and it correlates with MRI characteristics of 
      the pancreas itself, hemorrhage, abdominal wall, and infected collections.
FAU - Xiao, Bo
AU  - Xiao B
FAU - Xu, Hai-Bo
AU  - Xu HB
AD  - From the Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan.
FAU - Jiang, Zhi-Qiong
AU  - Jiang ZQ
AD  - Departments of Geratology.
FAU - Hu, Jin-Xiang
AU  - Hu JX
AD  - From the Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan.
FAU - Yang, Guo-Dong
AU  - Yang GD
AD  - Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 
      China.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Pancreas
JT  - Pancreas
JID - 8608542
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/analysis
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/blood/*complications
MH  - Edema/etiology
MH  - Female
MH  - Hemorrhage/etiology
MH  - Hospitalization
MH  - Humans
MH  - *Magnetic Resonance Imaging/methods
MH  - Male
MH  - Middle Aged
MH  - Pancreatitis/diagnostic imaging/*etiology
MH  - Pancreatitis, Acute Necrotizing/etiology
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Single-Blind Method
MH  - Tomography, X-Ray Computed
MH  - Young Adult
EDAT- 2020/04/14 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/04/14 06:00
PHST- 2020/04/14 06:00 [entrez]
PHST- 2020/04/14 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
AID - 00006676-202004000-00016 [pii]
AID - 10.1097/MPA.0000000000001530 [doi]
PST - ppublish
SO  - Pancreas. 2020 Apr;49(4):591-597. doi: 10.1097/MPA.0000000000001530.