PMID- 32284077 OWN - NLM STAT- MEDLINE DCOM- 20201104 LR - 20201104 IS - 1475-2662 (Electronic) IS - 0007-1145 (Linking) VI - 124 IP - 4 DP - 2020 Aug 28 TI - A detailed exploration of early infant milk feeding in a prospective birth cohort study in Ireland: combination feeding of breast milk and infant formula and early breast-feeding cessation. PG - 440-449 LID - 10.1017/S0007114520001324 [doi] AB - Breast-feeding initiation and continuation rates in the UK and Ireland are low relative to many European countries. As a core outcome of the prospective Cork Nutrition and Development Maternal-Infant Cohort (COMBINE) study (Cork, Ireland), we aimed to describe infant milk feeding practices in detail and examine the prevalence and impact of combination feeding of breast milk and infant formula on breast-feeding duration. COMBINE recruited 456 nulliparous mothers (2015-2017) for maternal-infant follow-up via interview at hospital discharge (median 3 (interquartile range (IQR) 2, 4) d (n 453)), 1 (n 418), 2 (n 392), 4 (n 366), 6 (n 362) and 9 (n 345) months of age. Median maternal age was 32 (IQR 29, 34) years, 97 % of mothers were of white ethnicity, 79 % were Irish-born and 75 % were college-educated. Overall, 75 % breastfed to any extent at discharge and 44 % breastfed solely. At 1, 2, 4, 6 and 9 months, respectively, 40, 36, 33, 24 and 19 % breastfed solely. Combination feeding of breast milk and infant formula was common at discharge (31 %) and 1 month (20 %). Reasons for combination feeding at 1 month included perceived/actual hunger (30 %), healthcare professional advice (31 %) and breast-feeding difficulties (13 %). Of mothers who breastfed to any extent at discharge, 45 % stopped within 4 months. Mothers who combination fed were more likely to cease breast-feeding than those who breastfed solely (relative risk 2.3 by 1 month and 12.0 by 2 months). These granular data provide valuable insight to early milk feeding practices and indicate that supporting early breast-feeding without formula use may be key to the successful continuation of breast-feeding. FAU - Hemmingway, Andrea AU - Hemmingway A AD - Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Republic of Ireland. AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. FAU - Fisher, Dawn AU - Fisher D AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. FAU - Berkery, Teresa AU - Berkery T AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. FAU - Dempsey, Eugene AU - Dempsey E AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. AD - Department of Paediatrics and Child Health, University College Cork, Cork, Republic of Ireland. FAU - Murray, Deirdre M AU - Murray DM AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. AD - Department of Paediatrics and Child Health, University College Cork, Cork, Republic of Ireland. FAU - Kiely, Mairead E AU - Kiely ME AD - Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Republic of Ireland. AD - INFANT Research Centre, University College Cork, Cork, Republic of Ireland. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200414 PL - England TA - Br J Nutr JT - The British journal of nutrition JID - 0372547 SB - IM MH - Adult MH - Bottle Feeding/*psychology MH - Breast Feeding/*psychology MH - Feeding Behavior/*psychology MH - Female MH - Humans MH - Infant MH - Infant Formula MH - Infant, Newborn MH - Ireland MH - Milk, Human MH - Mothers/*psychology MH - Pregnancy MH - Prospective Studies MH - Time Factors OTO - NOTNLM OT - Breast-feeding OT - Combination feeding OT - Infant feeding OT - Prospective birth cohorts EDAT- 2020/04/15 06:00 MHDA- 2020/11/05 06:00 CRDT- 2020/04/15 06:00 PHST- 2020/04/15 06:00 [pubmed] PHST- 2020/11/05 06:00 [medline] PHST- 2020/04/15 06:00 [entrez] AID - S0007114520001324 [pii] AID - 10.1017/S0007114520001324 [doi] PST - ppublish SO - Br J Nutr. 2020 Aug 28;124(4):440-449. doi: 10.1017/S0007114520001324. Epub 2020 Apr 14.