PMID- 32286011
OWN - NLM
STAT- MEDLINE
DCOM- 20210512
LR  - 20210512
IS  - 1467-789X (Electronic)
IS  - 1467-7881 (Print)
IS  - 1467-7881 (Linking)
VI  - 21
IP  - 8
DP  - 2020 Aug
TI  - Comparative effectiveness of bariatric surgeries in patients with obesity and 
      type 2 diabetes mellitus: A network meta-analysis of randomized controlled 
      trials.
PG  - e13030
LID - 10.1111/obr.13030 [doi]
LID - e13030
AB  - A network meta-analysis of randomized controlled trials (RCTs) was performed to 
      determine the hierarchies of different bariatric surgeries in patients with 
      obesity and type 2 diabetes mellitus (T2DM), in terms of diabetes remission and 
      cardiometabolic outcomes. Seventeen RCTs and six bariatric surgeries, including 
      single anastomosis (mini) gastric bypass (mini-GBP), biliopancreatic diversion 
      without duodenal switch (BPD), laparoscopic-adjustable gastric banding (LAGB), 
      laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGBP), greater 
      curvature plication (GCP) and nonsurgical treatments (NST) were included. 
      Mini-GBP, BPD, LSG, RYGBP and LAGB (from best to worst), as compared with NST, 
      were all significantly associated with the remission of T2DM. For the follow-up 
      period > 3 years, BPD, mini-GBP, RYGBP and LSG (from best to worst) were 
      significantly superior to NST in achieving the remission of T2DM. For secondary 
      outcomes, the overall ranking for bariatric surgeries was RYGBP > BPD > LSG > 
      LAGB after comprehensively weighting glucose, weight, systolic and diastolic 
      pressure, total cholesterol, triglycerides, high-density lipoprotein cholesterol 
      (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Mini-GBP has the 
      greatest probability of achieving diabetes remission in adults with obesity and 
      T2DM, yet BPD was the most effective in long-term diabetes remission. RYGBP 
      appears to be the most favourable alternative treatment to manage patients with 
      cardiometabolic conditions.
CI  - (c) 2020 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf 
      of World Obesity Federation.
FAU - Ding, Li
AU  - Ding L
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Fan, Yuxin
AU  - Fan Y
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Li, Hui
AU  - Li H
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Zhang, Yalan
AU  - Zhang Y
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Qi, Dongwang
AU  - Qi D
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Tang, Shaofang
AU  - Tang S
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Cui, Jingqiu
AU  - Cui J
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - He, Qing
AU  - He Q
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
FAU - Zhuo, Chuanjun
AU  - Zhuo C
AUID- ORCID: 0000-0002-3793-550X
AD  - Department of School of Mental Health, Jining Medical University, Jining, China.
FAU - Liu, Ming
AU  - Liu M
AD  - Department of Endocrinology and Metabolism, Tianjin Medical University General 
      Hospital, Tianjin, China.
LA  - eng
GR  - 17JCZDJC35700/Tianjin Municipal Science and Technology Commission/International
GR  - 17ZXMFSY00150/Tianjin Municipal Science and Technology Commission/International
GR  - 19JCQNJC11800/Tianjin Municipal Science and Technology Commission/International
GR  - 81620108004/National Natural Science Foundation of China/International
GR  - 81830025/National Natural Science Foundation of China/International
GR  - 81871052/National Natural Science Foundation of China/International
GR  - 2019YFA0802502/National Key R&D Program of China/International
PT  - Comparative Study
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20200414
PL  - England
TA  - Obes Rev
JT  - Obesity reviews : an official journal of the International Association for the 
      Study of Obesity
JID - 100897395
SB  - IM
MH  - Bariatric Surgery/*methods
MH  - Diabetes Mellitus, Type 2/*complications/*therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Network Meta-Analysis
MH  - Obesity/*complications/*surgery
MH  - Randomized Controlled Trials as Topic
MH  - Treatment Outcome
PMC - PMC7379237
OTO - NOTNLM
OT  - bariatric surgeries
OT  - cardiometabolic outcome
OT  - diabetes remission
OT  - network meta-analysis
COIS- The authors confirm that there are no conflicts of interest.
EDAT- 2020/04/15 06:00
MHDA- 2021/05/13 06:00
PMCR- 2020/07/24
CRDT- 2020/04/15 06:00
PHST- 2019/12/10 00:00 [received]
PHST- 2020/03/26 00:00 [revised]
PHST- 2020/03/26 00:00 [accepted]
PHST- 2020/04/15 06:00 [pubmed]
PHST- 2021/05/13 06:00 [medline]
PHST- 2020/04/15 06:00 [entrez]
PHST- 2020/07/24 00:00 [pmc-release]
AID - OBR13030 [pii]
AID - 10.1111/obr.13030 [doi]
PST - ppublish
SO  - Obes Rev. 2020 Aug;21(8):e13030. doi: 10.1111/obr.13030. Epub 2020 Apr 14.