PMID- 32288611
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1383-5866 (Print)
IS  - 1873-3794 (Electronic)
IS  - 1383-5866 (Linking)
VI  - 55
IP  - 3
DP  - 2007 Jul 1
TI  - Investigation on ultrasound assisted extraction of saikosaponins from Radix 
      Bupleuri.
PG  - 307-312
LID - 10.1016/j.seppur.2006.12.002 [doi]
AB  - Ultrasound assisted extraction (UAE) of saikosaponins from Radix Bupleuri 
      (Bupleurum Chinense DC) was studied. The effects of various factors such as time 
      (t), temperature (T), ultrasound power (I), particle size (S), solvent to solid 
      ratio (R) and solvent concentration (C) on the yield of target components were 
      investigated. The experimental results indicated that the extraction by UAE is 
      six times faster than those by conventional thermal extraction. It is also found 
      that fast extraction rate was obtained in the first 30 min of sonication. 
      Prolonged sonication did not give a proportional increase in the yield. For the 
      effect of ultrasound power, the maximum yield was obtained at the power level of 
      around 21 W. Scanning electron microscope (SEM) images of the plant cells after 
      UAE treatment were obtained to provide visual evidence of the sonication effect. 
      The effects of particle size, solvent to solid ratio and solvent concentration on 
      the yield are also discussed. The preliminary optimum conditions for UAE of 
      saikosaponins were found at time of 30 min, temperature of 80  degrees C, power of 21 W, 
      particle size <0.3 mm, solvent to solid ratio of 25 ml/g and solvent 
      concentration of 50%.
CI  - Copyright (c) 2007 Elsevier B.V. All rights reserved.
FAU - Zhao, Shuna
AU  - Zhao S
AD  - Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic 
      University, Kowloon, Hong Kong.
FAU - Kwok, Kin-Chor
AU  - Kwok KC
AD  - Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic 
      University, Kowloon, Hong Kong.
FAU - Liang, Hanhua
AU  - Liang H
AD  - Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic 
      University, Kowloon, Hong Kong.
LA  - eng
PT  - Journal Article
DEP - 20061215
PL  - Netherlands
TA  - Sep Purif Technol
JT  - Separation and purification technology
JID - 101526757
PMC - PMC7108326
OTO - NOTNLM
OT  - Extraction
OT  - Radix Bupleuri
OT  - Saikosaponins
OT  - Ultrasound
EDAT- 2007/07/01 00:00
MHDA- 2007/07/01 00:01
PMCR- 2006/12/15
CRDT- 2020/04/15 06:00
PHST- 2006/02/23 00:00 [received]
PHST- 2006/11/30 00:00 [revised]
PHST- 2006/12/02 00:00 [accepted]
PHST- 2020/04/15 06:00 [entrez]
PHST- 2007/07/01 00:00 [pubmed]
PHST- 2007/07/01 00:01 [medline]
PHST- 2006/12/15 00:00 [pmc-release]
AID - S1383-5866(06)00407-2 [pii]
AID - 10.1016/j.seppur.2006.12.002 [doi]
PST - ppublish
SO  - Sep Purif Technol. 2007 Jul 1;55(3):307-312. doi: 10.1016/j.seppur.2006.12.002. 
      Epub 2006 Dec 15.