PMID- 32290946
OWN - NLM
STAT- MEDLINE
DCOM- 20200826
LR  - 20200826
IS  - 1000-8020 (Print)
IS  - 1000-8020 (Linking)
VI  - 49
IP  - 2
DP  - 2020 Mar
TI  - [Determination of 1, 4-dioxane in aerosol cosmetic by new isotope 
      dilution-headspace gas chromatography-mass spectrometry].
PG  - 280-284
LID - 10.19813/j.cnki.weishengyanjiu.2020.02.019 [doi]
AB  - OBJECTIVE: To develop a simple, fast and sensitive analytical method based on 
      isotope dilution-headspace gas chromatography-mass spectrometry for the 
      determination of 1, 4-dioxane residue in the aerosol cosmetics. METHODS: Sample 
      was successive weighed and dissolved in 1, 
      3-dimehyl-2-imidazolidinone(DMI)solvent and isotope internal standard was added. 
      Then transfered to a 20 mL headspace vial. The headspace vial was sealed and 
      extracted 15 min by ultrasonic-assisted extraction. After separated by HP-5 MS 
      fused silica capillary column(30 mx25 mm, 0. 25 mum), the compound was analyzed by 
      gas chromatography-mass spectrometry in selected ion monitoring mode(GC-MS-SIM) 
      and quantified by internal standard method. RESULTS: There were good linear 
      correlations with R~2 no less than 0. 999 in the range of 1. 0-100 mg/kg. The 
      limit of detection(LOD) of this method was 0. 3 mg/kg. At 0. 3, 1. 0, 5. 0 and 30 
      mg/kg four added concentration, recovery for five kinds of aerosol cosmetic were 
      all between 91. 4% and 104. 2%. The relative standard deviations(RSDs) were 1. 
      5%-6. 3% and 1. 7%-6. 4%(n=6), respectively. CONCLUSION: The developed method has 
      proved convenient, time-saving, accurate and sensitive and suited for 
      determination 1, 4-dioxane in aerosol cosmetic.
FAU - Rong, Weiguang
AU  - Rong W
AD  - Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, 
      China.
FAU - Zhu, Minghong
AU  - Zhu M
AD  - Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, 
      China.
FAU - Ji, Wenliang
AU  - Ji W
AD  - Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, 
      China.
FAU - Liu, Hualiang
AU  - Liu H
AD  - Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, 
      China.
FAU - Huo, Zongli
AU  - Huo Z
AD  - Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, 
      China.
FAU - Song, Ninghui
AU  - Song N
AD  - Nanjing Institute of Environment Science, Department of Environmental Protection, 
      Nanjing 210042, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Wei Sheng Yan Jiu
JT  - Wei sheng yan jiu = Journal of hygiene research
JID - 9426367
RN  - 0 (Aerosols)
RN  - 0 (Cosmetics)
RN  - 0 (Dioxanes)
SB  - IM
MH  - Aerosols
MH  - Cosmetics/*analysis
MH  - Dioxanes
MH  - Gas Chromatography-Mass Spectrometry
MH  - Mass Spectrometry
OTO - NOTNLM
OT  - 1, 4-dioxane
OT  - aerosol cosmetic
OT  - headspace gas chromatography-mass spectrometry
EDAT- 2020/04/16 06:00
MHDA- 2020/08/28 06:00
CRDT- 2020/04/16 06:00
PHST- 2020/04/16 06:00 [entrez]
PHST- 2020/04/16 06:00 [pubmed]
PHST- 2020/08/28 06:00 [medline]
AID - 10.19813/j.cnki.weishengyanjiu.2020.02.019 [doi]
PST - ppublish
SO  - Wei Sheng Yan Jiu. 2020 Mar;49(2):280-284. doi: 
      10.19813/j.cnki.weishengyanjiu.2020.02.019.