PMID- 32292077
OWN - NLM
STAT- MEDLINE
DCOM- 20210809
LR  - 20210809
IS  - 1744-8417 (Electronic)
IS  - 1744-6651 (Linking)
VI  - 15
IP  - 3
DP  - 2020 May
TI  - Long-term outcomes of bariatric surgery in patients with diabetes.
PG  - 141-146
LID - 10.1080/17446651.2020.1754191 [doi]
AB  - Introduction: Initially seen as a weight-loss operation, bariatric surgery is now 
      recognized as a metabolic procedure with a critical role in the management of 
      type 2 diabetes mellitus (T2DM). Early improvement in glucose metabolism is a 
      remarkable effect of surgery; however, what deserves equal thought are 
      implications for long-term diabetes control and relapse. Evidence suggests the 
      metabolic effects of surgery fatigue and a proportion of patients will experience 
      relapse of T2DM, with or without weight regain. Herein, we discuss the evidence 
      examining the durability of these effects and approaches to improve long-term 
      control.Areas covered: PubMed, Embase, CENTRAL, and Medline were searched for 
      trials looking at outcomes for patients with obesity and T2DM undergoing 
      bariatric surgery between January 2000 andDecember 2019. Additional studies were 
      found by searching publications from related journals and references.Export 
      opinion: Bariatric surgery is a safe and effective treatment for T2DM and obesity 
      however the response to surgery, like any other treatment is variable. Some 
      patients will experience a relapse of diabetes in the long term. Recent 
      developments in pharmacotherapy present an opportunity to augment or sustain what 
      can be achieved with surgery. Combinational treatment may dramatically change the 
      way both diseases are managed.
FAU - Sudlow, Alexis C
AU  - Sudlow AC
AUID- ORCID: 0000-0002-9040-0803
AD  - Department of Upper GI Surgery, Southmead Hospital, Bristol, UK.
FAU - Le Roux, Carel W
AU  - Le Roux CW
AUID- ORCID: 0000-0001-5521-5445
AD  - Department of Experimental Pathology, University College Dublin, Dublin, Ireland.
FAU - Pournaras, Dimitri J
AU  - Pournaras DJ
AD  - Department of Upper GI Surgery, Southmead Hospital, Bristol, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200415
PL  - England
TA  - Expert Rev Endocrinol Metab
JT  - Expert review of endocrinology & metabolism
JID - 101278293
SB  - IM
MH  - *Bariatric Surgery
MH  - Diabetes Mellitus, Type 2/etiology/metabolism/*therapy
MH  - Humans
MH  - Obesity/complications/metabolism/*surgery
MH  - Randomized Controlled Trials as Topic
MH  - Treatment Outcome
MH  - Weight Loss/*physiology
OTO - NOTNLM
OT  - Obesity
OT  - bariatric surgery
OT  - multi-modal care
OT  - type 2 diabetes mellitus
OT  - weight-loss pharmacotherapy
EDAT- 2020/04/16 06:00
MHDA- 2021/08/10 06:00
CRDT- 2020/04/16 06:00
PHST- 2020/04/16 06:00 [pubmed]
PHST- 2021/08/10 06:00 [medline]
PHST- 2020/04/16 06:00 [entrez]
AID - 10.1080/17446651.2020.1754191 [doi]
PST - ppublish
SO  - Expert Rev Endocrinol Metab. 2020 May;15(3):141-146. doi: 
      10.1080/17446651.2020.1754191. Epub 2020 Apr 15.