PMID- 32296979
OWN - NLM
STAT- MEDLINE
DCOM- 20210427
LR  - 20210427
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Print)
IS  - 0937-4477 (Linking)
VI  - 277
IP  - 8
DP  - 2020 Aug
TI  - Swallow-related quality of life and oropharyngeal dysphagia in myotonic 
      dystrophy.
PG  - 2357-2362
LID - 10.1007/s00405-020-05964-2 [doi]
AB  - PURPOSE: This study describes swallow-related quality of life (SWAL-QOL) in 
      patients with myotonic dystrophy type 1 (DM1) and investigates its association 
      with swallowing function and disease severity. METHODS: A SWAL-QOL questionnaire 
      was completed by 75 DM1 patients and 25 healthy control subjects. The severity of 
      the disease was evaluated using the muscular impairment rating scale (MIRS). 
      Twenty-eight DM1 patients underwent a videofluroscopic swallowing examination 
      (VFS). Spearman's correlation coefficient was used to measure the direction and 
      strength of associations. RESULTS: The SWAL-QOL median scores were significantly 
      lower for the DM1 group than for the healthy control group. The scores for the 
      majority of the SWAL-QOL domains were lower in patients with proximal muscular 
      weakness (MIRS 4 and 5). Postswallow vallecular pooling and piecemeal deglutition 
      were the most impaired VFS outcome variables. CONCLUSION: Our results suggest 
      that a multidimensional swallowing assessment is recommended for DM1 patients as 
      SWAL-QOL and VFS measure different aspects of the swallowing function, thus 
      providing complementary information.
FAU - Pilz, Walmari
AU  - Pilz W
AUID- ORCID: 0000-0002-3914-5587
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University 
      Medical Center, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands. 
      w.pilz@mumc.nl.
AD  - School for Mental Health and Neuroscience, MHeNs, Maastricht University, 
      Maastricht, The Netherlands. w.pilz@mumc.nl.
FAU - Passos, Valeria Lima
AU  - Passos VL
AD  - Department of Methodology and Statistics, Maastricht University, Maastricht, The 
      Netherlands.
AD  - School for Public Health and Primary Care, CAPHRI, Maastricht University, 
      Maastricht, The Netherlands.
FAU - Verdonschot, Rob J
AU  - Verdonschot RJ
AD  - Emergency Department, Erasmus Medical Center, Rotterdam, The Netherlands.
FAU - Meijers, Jolanda
AU  - Meijers J
AD  - Department of Radiology, Maastricht University Medical Center, Maastricht, The 
      Netherlands.
FAU - Roodenburg, Nel
AU  - Roodenburg N
AD  - Department of Neurology, Maastricht University Medical Center, Maastricht, The 
      Netherlands.
FAU - Halmans, Yana
AU  - Halmans Y
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University 
      Medical Center, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
FAU - Faber, Catharina G
AU  - Faber CG
AD  - Department of Neurology, Maastricht University Medical Center, Maastricht, The 
      Netherlands.
FAU - Kremer, Bernd
AU  - Kremer B
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University 
      Medical Center, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
AD  - School for Oncology and Developmental Biology, GROW, Maastricht University, 
      Maastricht, The Netherlands.
FAU - Baijens, Laura W J
AU  - Baijens LWJ
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University 
      Medical Center, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
AD  - School for Oncology and Developmental Biology, GROW, Maastricht University, 
      Maastricht, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20200415
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
SB  - IM
MH  - Deglutition
MH  - *Deglutition Disorders/diagnosis/etiology
MH  - Humans
MH  - *Myotonic Dystrophy/complications
MH  - Quality of Life
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
PMC - PMC7335374
OTO - NOTNLM
OT  - Deglutition disorders
OT  - Dysphagia
OT  - Myotonic dystrophy
OT  - Quality of life
OT  - Videofluoroscopy
COIS- The authors declare that they have no conflict of interest.
EDAT- 2020/04/17 06:00
MHDA- 2021/04/28 06:00
PMCR- 2020/04/15
CRDT- 2020/04/17 06:00
PHST- 2020/03/04 00:00 [received]
PHST- 2020/04/01 00:00 [accepted]
PHST- 2020/04/17 06:00 [pubmed]
PHST- 2021/04/28 06:00 [medline]
PHST- 2020/04/17 06:00 [entrez]
PHST- 2020/04/15 00:00 [pmc-release]
AID - 10.1007/s00405-020-05964-2 [pii]
AID - 5964 [pii]
AID - 10.1007/s00405-020-05964-2 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2357-2362. doi: 
      10.1007/s00405-020-05964-2. Epub 2020 Apr 15.