PMID- 3229865 OWN - NLM STAT- MEDLINE DCOM- 19890414 LR - 20190816 IS - 0167-5273 (Print) IS - 0167-5273 (Linking) VI - 21 IP - 3 DP - 1988 Dec TI - Dilated cardiomyopathy: long-term follow-up and predictors of survival. PG - 269-77 AB - To determine long-term survival and the prognostic factors of dilated cardiomyopathy, we retrospectively studied a consecutive series of 111 patients (95 men, 16 women, mean age: 45.5 +/- 8.1 years) undergoing cardiac catheterization and diagnostic coronary angiography from January 1970 to December 1979. The inclusion criteria were: normal coronary angiography, diffuse hypokinesia of the left ventricle and left ventricular ejection fraction less than 50%. Base-line clinical data were collected from the hospital records and follow-up data were obtained from the general practitioners and cardiologists. A questionnaire was sent to all living patients. The length of follow-up ranged from 6 to 16 years. Six patients (5%) were lost to follow-up. At the time of catheterization, a majority of the patients had dyspnea and were in New York Heart Association (NYHA) classes II (41%) and III (31%). Clinical history revealed an excessive alcohol consumption in 56% of the patients. During follow-up, 66 patients (63%) died (heart failure: 37%; sudden death: 19%; non-cardiac death: 15%; unknown cause: 27%). Actuarial survival was 90, 50, and 33% at 1, 5, and 10 years, respectively. Univariate analysis revealed that 10-year mortality was related to: left ventricular ejection fraction less than 30%; left ventricular end-diastolic pressure greater than 10 mm Hg; cardiothoracic ratio greater than 54%; episodes of heart failure; left ventricular end-diastolic volume greater than 200 ml/m2, dyspnea of NYHA class III or IV; absence of smoking; absence of moderate systemic hypertension; electrocardiographic evidence of left ventricular hypertrophy and mean systemic arterial pressure greater than 95 mm Hg.(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Juilliere, Y AU - Juilliere Y AD - Cardiologie B, CHU Nancy-Brabois, France. FAU - Danchin, N AU - Danchin N FAU - Briancon, S AU - Briancon S FAU - Khalife, K AU - Khalife K FAU - Ethevenot, G AU - Ethevenot G FAU - Balaud, A AU - Balaud A FAU - Gilgenkrantz, J M AU - Gilgenkrantz JM FAU - Pernot, C AU - Pernot C FAU - Cherrier, F AU - Cherrier F LA - eng PT - Journal Article PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Adult MH - Blood Pressure MH - Cardiac Catheterization MH - Cardiomyopathy, Dilated/*diagnosis/mortality/physiopathology MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Stroke Volume EDAT- 1988/12/01 00:00 MHDA- 1988/12/01 00:01 CRDT- 1988/12/01 00:00 PHST- 1988/12/01 00:00 [pubmed] PHST- 1988/12/01 00:01 [medline] PHST- 1988/12/01 00:00 [entrez] AID - 0167-5273(88)90104-0 [pii] AID - 10.1016/0167-5273(88)90104-0 [doi] PST - ppublish SO - Int J Cardiol. 1988 Dec;21(3):269-77. doi: 10.1016/0167-5273(88)90104-0.