PMID- 32300450 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 1927-1212 (Print) IS - 1927-1220 (Electronic) IS - 1927-1212 (Linking) VI - 8 IP - 2 DP - 2019 Jun TI - Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report. PG - 83-85 LID - 10.14740/jh519 [doi] AB - Arterial occlusive events (AOEs) such as cerebrovascular, cardiovascular and peripheral arterial events are known side effects of ponatinib, assumed due to the rapid development and increase of arteriosclerosis, while the definitive pathomechanisms therefore are still unclear. We present a case of clinically apparent large vessel vasculitis and discuss this phenomenon as a possible mechanism of AOEs beside arteriosclerosis. CI - Copyright 2019, Hirschbuehl et al. FAU - Hirschbuehl, Klaus AU - Hirschbuehl K AD - Department of Hematology and Oncology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Rank, Andreas AU - Rank A AD - Department of Hematology and Oncology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Pfeiffer, Tim AU - Pfeiffer T AD - Department of Hematology and Oncology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Schaller, Tina AU - Schaller T AD - Institute of Pathology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Haeckel, Thomas AU - Haeckel T AD - Department of Radiology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Roeling, Joerg AU - Roeling J AD - Internistische Gemeinschaftspraxis am Vincentinum, Franziskanergasse 14, 86152 Augsburg, Germany. FAU - Vlasenko, Dmytro AU - Vlasenko D AD - Department of Visceral Surgery, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Trepel, Martin AU - Trepel M AD - Department of Hematology and Oncology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. FAU - Schmid, Christoph AU - Schmid C AD - Department of Hematology and Oncology, Universitaetsklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg, Germany. LA - eng PT - Case Reports DEP - 20190630 PL - Canada TA - J Hematol JT - Journal of hematology JID - 101635099 PMC - PMC7153681 OTO - NOTNLM OT - Arterial occlusive events OT - Ponatinib OT - Vasculitis COIS- The authors declare no conflict of interest. EDAT- 2020/04/18 06:00 MHDA- 2020/04/18 06:01 PMCR- 2019/06/01 CRDT- 2020/04/18 06:00 PHST- 2019/05/13 00:00 [received] PHST- 2019/06/07 00:00 [accepted] PHST- 2020/04/18 06:00 [entrez] PHST- 2020/04/18 06:00 [pubmed] PHST- 2020/04/18 06:01 [medline] PHST- 2019/06/01 00:00 [pmc-release] AID - 10.14740/jh519 [doi] PST - ppublish SO - J Hematol. 2019 Jun;8(2):83-85. doi: 10.14740/jh519. Epub 2019 Jun 30.