PMID- 32304871
OWN - NLM
STAT- MEDLINE
DCOM- 20201209
LR  - 20201214
IS  - 1532-0456 (Print)
IS  - 1532-0456 (Linking)
VI  - 233
DP  - 2020 Jul
TI  - Immune and physiological responses of mud crab (Scylla paramamosain) under air 
      exposure.
PG  - 108767
LID - S1532-0456(20)30067-3 [pii]
LID - 10.1016/j.cbpc.2020.108767 [doi]
AB  - The immune and physiological responses of mud crab (Scylla paramamosain) under 
      air exposure were studied. The results showed that air exposure increased plasma 
      activities of AST, ALT, ALP. There was a significant increase in glucose (GLU) 
      and malondialdehyde (MDA) levels after air exposure. The transcript levels of 
      SOD, CAT, HSP90, HSP70, p53, and hypoxia-inducible factor-1 (HIF-1) were induced 
      by air exposure. Furthermore, caspase-3 transcript significantly increased at 48 
      and 72 h, while it significantly decreased at 96 h and 120 h under air exposure. 
      These results suggested that oxidative stress occurred in the prolonged period of 
      air exposure. HIF-1 and p53 signaling pathways played an important role under air 
      exposure.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Cheng, Chang-Hong
AU  - Cheng CH
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China.
FAU - Ma, Hong-Ling
AU  - Ma HL
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China.
FAU - Deng, Yi-Qin
AU  - Deng YQ
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China.
FAU - Feng, Juan
AU  - Feng J
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China.
FAU - Jie, Yu-Kun
AU  - Jie YK
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China.
FAU - Guo, Zhi-Xun
AU  - Guo ZX
AD  - Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, 
      Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese 
      Academy of Fishery Sciences, Guangzhou, Guangdong 510300, PR China. Electronic 
      address: guozhixun1@163.com.
LA  - eng
PT  - Journal Article
DEP - 20200415
PL  - United States
TA  - Comp Biochem Physiol C Toxicol Pharmacol
JT  - Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
JID - 100959500
RN  - 0 (Arthropod Proteins)
RN  - 0 (HSP70 Heat-Shock Proteins)
RN  - 0 (HSP90 Heat-Shock Proteins)
RN  - 0 (Hypoxia-Inducible Factor 1)
RN  - 0 (Reactive Oxygen Species)
RN  - 0 (Tumor Suppressor Protein p53)
SB  - IM
MH  - *Air
MH  - Animals
MH  - Arthropod Proteins/*metabolism
MH  - Brachyura/immunology/*physiology
MH  - HSP70 Heat-Shock Proteins/metabolism
MH  - HSP90 Heat-Shock Proteins/metabolism
MH  - Hypoxia-Inducible Factor 1/metabolism
MH  - *Oxidative Stress
MH  - Reactive Oxygen Species/metabolism
MH  - Tumor Suppressor Protein p53/metabolism
OTO - NOTNLM
OT  - Air exposure
OT  - Immune response
OT  - Mud crab
COIS- Declaration of competing interest The authors declared that they have no 
      conflicts of interest to this work. We declare that we do not have any commercial 
      or associative interest that represents a conflict of interest in connection with 
      the work submitted.
EDAT- 2020/04/19 06:00
MHDA- 2020/12/15 06:00
CRDT- 2020/04/19 06:00
PHST- 2020/01/04 00:00 [received]
PHST- 2020/04/01 00:00 [revised]
PHST- 2020/04/11 00:00 [accepted]
PHST- 2020/04/19 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/04/19 06:00 [entrez]
AID - S1532-0456(20)30067-3 [pii]
AID - 10.1016/j.cbpc.2020.108767 [doi]
PST - ppublish
SO  - Comp Biochem Physiol C Toxicol Pharmacol. 2020 Jul;233:108767. doi: 
      10.1016/j.cbpc.2020.108767. Epub 2020 Apr 15.