PMID- 32307105
OWN - NLM
STAT- MEDLINE
DCOM- 20200731
LR  - 20200731
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1622
DP  - 2020 Jul 5
TI  - Application of full scan gas chromatography high resolution mass spectrometry 
      data to quantify targeted-pesticide residues and to screen for additional 
      substances of concern in fresh-food commodities.
PG  - 461118
LID - S0021-9673(20)30349-6 [pii]
LID - 10.1016/j.chroma.2020.461118 [doi]
AB  - A novel application, which combines targeted and non-targeted approaches, using 
      gas chromatography high-resolution mass spectrometry (GCHRMS) for multiresidue 
      analysis of pesticides in fruits and vegetables is proposed; the aim is to add 
      information to that obtained from targeted methods to be used in pesticide 
      residues monitoring laboratories. Extract from fruit samples obtained with 
      QuEChERS method are analysed with two different approaches: a first step in 
      targeted mode in full scan, and a second step in non-targeted mode with HRMS 
      deconvolution. The targeted method was validated for 191 pesticides, in banana, 
      watermelon, pear and strawberry, with recoveries within 70-120%, precision-RSD 
      <20%, linearity between 1-100 microg/kg (5-100 microg/kg in strawberry) and 
      quantification limits (LOQs) of 5 microg/kg. For targeted method, 12 different 
      pesticides in 14 samples were detected. The non-targeted approach allowed the 
      corroboration of all the results obtained through targeted method, in addition 
      other compounds were tentatively identified.
CI  - Copyright (c) 2020. Published by Elsevier B.V.
FAU - Vargas-Perez, Marta
AU  - Vargas-Perez M
AD  - Research Group "Analytical Chemistry of Contaminants", Department of Chemistry 
      and Physics, Center for Research in Mediterranean Intensive Agrosystems and 
      Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of 
      International Excellence, CeiA3, E-04120 Almeria Spain.
FAU - Dominguez, Irene
AU  - Dominguez I
AD  - Research Group "Analytical Chemistry of Contaminants", Department of Chemistry 
      and Physics, Center for Research in Mediterranean Intensive Agrosystems and 
      Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of 
      International Excellence, CeiA3, E-04120 Almeria Spain.
FAU - Gonzalez, Francisco Javier Egea
AU  - Gonzalez FJE
AD  - Research Group "Analytical Chemistry of Contaminants", Department of Chemistry 
      and Physics, Center for Research in Mediterranean Intensive Agrosystems and 
      Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of 
      International Excellence, CeiA3, E-04120 Almeria Spain.
FAU - Frenich, Antonia Garrido
AU  - Frenich AG
AD  - Research Group "Analytical Chemistry of Contaminants", Department of Chemistry 
      and Physics, Center for Research in Mediterranean Intensive Agrosystems and 
      Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of 
      International Excellence, CeiA3, E-04120 Almeria Spain. Electronic address: 
      agarrido@ual.es.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20200413
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Food Contamination/analysis
MH  - Fruit/*chemistry
MH  - *Gas Chromatography-Mass Spectrometry
MH  - Pesticide Residues/*analysis
MH  - Vegetables/*chemistry
OTO - NOTNLM
OT  - Deconvolution
OT  - Full-scan
OT  - Gas chromatography
OT  - HRMS
OT  - Pesticide residues monitoring
OT  - Q-Exactive Orbitrap
COIS- Declaration of competing interests The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/04/21 06:00
MHDA- 2020/08/01 06:00
CRDT- 2020/04/21 06:00
PHST- 2020/01/19 00:00 [received]
PHST- 2020/03/24 00:00 [revised]
PHST- 2020/04/06 00:00 [accepted]
PHST- 2020/04/21 06:00 [pubmed]
PHST- 2020/08/01 06:00 [medline]
PHST- 2020/04/21 06:00 [entrez]
AID - S0021-9673(20)30349-6 [pii]
AID - 10.1016/j.chroma.2020.461118 [doi]
PST - ppublish
SO  - J Chromatogr A. 2020 Jul 5;1622:461118. doi: 10.1016/j.chroma.2020.461118. Epub 
      2020 Apr 13.