PMID- 32309761 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220414 IS - 2472-7245 (Electronic) IS - 2472-7245 (Linking) VI - 5 IP - 1 DP - 2020 Jan-Mar TI - Use of Computerized Adaptive Testing to Develop More Concise Patient-Reported Outcome Measures. PG - e0052 LID - 10.2106/JBJS.OA.19.00052 [doi] LID - e0052 AB - BACKGROUND: Patient-reported outcome measures (PROMs) are essential tools that are used to assess health status and treatment outcomes in orthopaedic care. Use of PROMs can burden patients with lengthy and cumbersome questionnaires. Predictive models using machine learning known as computerized adaptive testing (CAT) offer a potential solution. The purpose of this study was to evaluate the ability of CAT to improve efficiency of the Veterans RAND 12 Item Health Survey (VR-12) by decreasing the question burden while maintaining the accuracy of the outcome score. METHODS: A previously developed CAT model was applied to the responses of 19,523 patients who had completed a full VR-12 survey while presenting to 1 of 5 subspecialty orthopaedic clinics. This resulted in the calculation of both a full-survey and CAT-model physical component summary score (PCS) and mental component summary score (MCS). Several analyses compared the accuracy of the CAT model scores with that of the full scores by comparing the means and standard deviations, calculating a Pearson correlation coefficient and intraclass correlation coefficient, plotting the frequency distributions of the 2 score sets and the score differences, and performing a Bland-Altman assessment of scoring patterns. RESULTS: The CAT model required 4 fewer questions to be answered by each subject (33% decrease in question burden). The mean PCS was 1.3 points lower in the CAT model than with the full VR-12 (41.5 +/- 11.0 versus 42.8 +/- 10.4), and the mean MCS was 0.3 point higher (57.3 +/- 9.4 versus 57.0 +/- 9.6). The Pearson correlation coefficients were 0.97 for PCS and 0.98 for MCS, and the intraclass correlation coefficients were 0.96 and 0.97, respectively. The frequency distribution of the CAT and full scores showed significant overlap for both the PCS and the MCS. The difference between the CAT and full scores was less than the minimum clinically important difference (MCID) in >95% of cases for the PCS and MCS. CONCLUSIONS: The application of CAT to the VR-12 survey demonstrated an ability to lessen the response burden for patients with a negligible effect on score integrity. CI - Copyright (c) 2020 The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated. All rights reserved. FAU - Kane, Liam T AU - Kane LT AD - Rothman Orthopaedic Institute, Philadelphia, Pennsylvania. FAU - Namdari, Surena AU - Namdari S AD - Rothman Orthopaedic Institute, Philadelphia, Pennsylvania. FAU - Plummer, Otho R AU - Plummer OR AD - Universal Research Solutions, Columbia, Missouri. FAU - Beredjiklian, Pedro AU - Beredjiklian P AD - Rothman Orthopaedic Institute, Philadelphia, Pennsylvania. FAU - Vaccaro, Alexander AU - Vaccaro A AD - Rothman Orthopaedic Institute, Philadelphia, Pennsylvania. FAU - Abboud, Joseph A AU - Abboud JA AD - Rothman Orthopaedic Institute, Philadelphia, Pennsylvania. LA - eng PT - Journal Article DEP - 20200312 PL - United States TA - JB JS Open Access JT - JB & JS open access JID - 101726219 PMC - PMC7147635 EDAT- 2020/04/21 06:00 MHDA- 2020/04/21 06:01 PMCR- 2020/03/12 CRDT- 2020/04/21 06:00 PHST- 2020/04/21 06:00 [entrez] PHST- 2020/04/21 06:00 [pubmed] PHST- 2020/04/21 06:01 [medline] PHST- 2020/03/12 00:00 [pmc-release] AID - JBJSOA-D-19-00052 [pii] AID - 10.2106/JBJS.OA.19.00052 [doi] PST - epublish SO - JB JS Open Access. 2020 Mar 12;5(1):e0052. doi: 10.2106/JBJS.OA.19.00052. eCollection 2020 Jan-Mar.