PMID- 32311979
OWN - NLM
STAT- MEDLINE
DCOM- 20200424
LR  - 20221005
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 99
IP  - 16
DP  - 2020 Apr
TI  - Prevalence of osteoporosis in patients with type 2 diabetes mellitus in the 
      Chinese mainland: A protocol of systematic review and meta-analysis.
PG  - e19762
LID - 10.1097/MD.0000000000019762 [doi]
LID - e19762
AB  - BACKGROUND: Osteoporosis, as a metabolic disease, has become one of the most 
      rapidly growing complications of diabetes mellitus. Previously, we conducted a 
      systematic review to report the estimated prevalence of osteoporosis among 
      patients with type 2 diabetes mellitus (T2DM) from 2001 to 2016. However, some 
      newer studies have been reported, and more potential risk factors for 
      osteoporosis remain controversial and vague. Therefore, the presented review is 
      tailored to synthesize available evidence regarding the pooled prevalence and 
      related risk factors of osteoporosis among T2DM patients in mainland China. 
      METHODS: Both cross-sectional study and cohort study reporting on the prevalence 
      of osteoporosis among patients with T2DM in mainland China, published in Chinese 
      or English, will be considered for inclusion. Records from 4 English databases 
      and 2 Chinese databases will be retrieved from their inceptions to March 2020. 
      The process of study selection, data extraction, and methodologic quality 
      assessment will be independently executed by 2 reviewers. The pooled prevalence 
      of osteoporosis and the prevalence in the exposed and unexposed groups for each 
      potential risk factor will be calculated by the software Stata version 12.0. 
      RESULTS: The current systematic review and meta-analysis will provide more 
      precise prevalence rates and associated risk factors of osteoporosis among people 
      with T2DM in mainland China. CONCLUSION: The study will offer high-quality and 
      explicit evidence for assisting diabetic patients to prevent osteoporosis in 
      mainland China. OSF REGISTRATION: DOI 10.17605/OSF.IO/5ZKJ6.
FAU - Si, Yuhao
AU  - Si Y
AD  - The First School of Clinical Medicine, Laboratory for New Techniques of 
      Restoration & Reconstruction of Orthopedics and Traumatology, Nanjing University 
      of Chinese Medicine, Nanjing.
AD  - Rangos School of Health Sciences, Duquesne University, Pittsburgh, USA.
FAU - Wang, Cenyi
AU  - Wang C
AD  - Department of Rehabilitation, The First Affiliated Hospital of Guangxi University 
      of Chinese Medicine, Nanning, China.
AD  - Rangos School of Health Sciences, Duquesne University, Pittsburgh, USA.
FAU - Guo, Yang
AU  - Guo Y
AD  - The First School of Clinical Medicine, Laboratory for New Techniques of 
      Restoration & Reconstruction of Orthopedics and Traumatology, Nanjing University 
      of Chinese Medicine, Nanjing.
FAU - Yin, Heng
AU  - Yin H
AD  - Department of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing 
      University of Chinese Medicine, Wuxi.
FAU - Ma, Yong
AU  - Ma Y
AD  - The First School of Clinical Medicine, Laboratory for New Techniques of 
      Restoration & Reconstruction of Orthopedics and Traumatology, Nanjing University 
      of Chinese Medicine, Nanjing.
AD  - Affiliated Hospital of Nanjing University of Chinese Medicine, Department of 
      Traumatology & Orthopedics, Nanjing.
AD  - College of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 
      China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - China/epidemiology
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Humans
MH  - Meta-Analysis as Topic
MH  - Osteoporosis/complications/*epidemiology
MH  - Prevalence
MH  - Systematic Reviews as Topic
PMC - PMC7220203
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2020/04/22 06:00
MHDA- 2020/04/25 06:00
PMCR- 2020/04/17
CRDT- 2020/04/22 06:00
PHST- 2020/04/22 06:00 [entrez]
PHST- 2020/04/22 06:00 [pubmed]
PHST- 2020/04/25 06:00 [medline]
PHST- 2020/04/17 00:00 [pmc-release]
AID - 00005792-202004170-00063 [pii]
AID - MD-D-20-02004 [pii]
AID - 10.1097/MD.0000000000019762 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2020 Apr;99(16):e19762. doi: 10.1097/MD.0000000000019762.