PMID- 32313475
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 0899-8280 (Print)
IS  - 1525-3252 (Electronic)
IS  - 0899-8280 (Linking)
VI  - 33
IP  - 2
DP  - 2020 Apr
TI  - Human herpesvirus 6 meningitis in an adult.
PG  - 246-247
LID - 10.1080/08998280.2020.1719784 [doi]
AB  - Many cases of viral meningitis are idiopathic, but increased utilization of 
      polymerase chain reaction testing has enabled physicians to better recognize rare 
      causes of viral meningitis. This will likely continue to improve the rate of 
      causative agent identification in seemingly idiopathic viral meningitis, 
      including this case of human herpesvirus 6 (HHV-6) meningitis in an 
      immunocompetent adult patient. More common viral etiologies need to be excluded 
      before diagnosing HHV-6 meningitis, as this maximizes pretest probability and 
      therefore increases validity of a positive result. By efficiently diagnosing 
      HHV-6 meningitis, proper treatment protocols can be initiated earlier to reduce 
      morbidity and mortality. Given the rarity of HHV-6 meningitis in immunocompetent 
      adults, there are no established standard treatment guidelines; previous reported 
      cases, as well as this case, suggest that either intravenous ganciclovir or 
      intravenous foscarnet are the most reasonable first-line treatment options.
CI  - Copyright (c) 2020 Baylor University Medical Center.
FAU - Maniam, Ganesh B
AU  - Maniam GB
AUID- ORCID: 0000-0002-4217-9489
AD  - School of Medicine, Texas Tech University Health Sciences CenterAmarilloTexas.
FAU - Wilkerson, Hannah
AU  - Wilkerson H
AD  - School of Medicine, Texas Tech University Health Sciences CenterAmarilloTexas.
FAU - Milton, John Scott
AU  - Milton JS
AD  - Department of Internal Medicine, Texas Tech University Health Sciences 
      CenterAmarilloTexas.
LA  - eng
PT  - Case Reports
DEP - 20200127
PL  - United States
TA  - Proc (Bayl Univ Med Cent)
JT  - Proceedings (Baylor University. Medical Center)
JID - 9302033
PMC - PMC7155960
OTO - NOTNLM
OT  - HHV-6
OT  - infectious disease
OT  - meningitis
OT  - polymerase chain reaction
OT  - viral meningitis
EDAT- 2020/04/22 06:00
MHDA- 2020/04/22 06:01
PMCR- 2020/01/27
CRDT- 2020/04/22 06:00
PHST- 2019/11/11 00:00 [received]
PHST- 2020/01/15 00:00 [revised]
PHST- 2020/01/20 00:00 [accepted]
PHST- 2020/04/22 06:00 [entrez]
PHST- 2020/04/22 06:00 [pubmed]
PHST- 2020/04/22 06:01 [medline]
PHST- 2020/01/27 00:00 [pmc-release]
AID - 1719784 [pii]
AID - 10.1080/08998280.2020.1719784 [doi]
PST - epublish
SO  - Proc (Bayl Univ Med Cent). 2020 Jan 27;33(2):246-247. doi: 
      10.1080/08998280.2020.1719784. eCollection 2020 Apr.