PMID- 32314246 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20200423 LR - 20201031 IS - 1436-5073 (Electronic) IS - 0026-3672 (Linking) VI - 187 IP - 5 DP - 2020 Apr 20 TI - A "half" core-shell magnetic nanohybrid composed of zeolitic imidazolate framework and graphitic carbon nitride for magnetic solid-phase extraction of sulfonylurea herbicides from water samples followed by LC-MS/MS detection. PG - 279 LID - 10.1007/s00604-020-04243-5 [doi] AB - A "half" core-shell g-C(3)N(4)/Fe(3)O(4)@ZIF-8 nanohybrid, in which Fe(3)O(4) and zeolite imidazolate framework-8 (ZIF-8) constructed the core-shell structure, was successfully fabricated via a versatile in situ growth strategy. This nanohybrid was employed for simultaneous magnetic solid-phase extraction (MSPE) of trace levels of fifteen target sulfonylurea herbicides (SUHs) in environmental water samples followed by LC-MS/MS detection. C(3)N(4) nanosheets were first prepared by liquid exfoliation of bulk g-C(3)N(4), after which Fe(3)O(4) nanoparticles were uniformly deposited onto the surface of C(3)N(4) nanosheets, and ZIF-8 nanoparticles were grown on the surface of g-C(3)N(4)/Fe(3)O(4) by anchoring Zn(2+) on g-C(3)N(4)/Fe(3)O(4). Owing to the synergistic effect, the hybridization of C(3)N(4) and ZIF-8 endowed the nanohybrid with higher multi-target adsorption ability for SUHs compared to pure C(3)N(4) or ZIF-8. The separation as well as the enrichment processes were facilitated using Fe(3)O(4) as a magnetic core. The influence of various parameters on MSPE efficiency, including adsorbent dosage, extraction time, solution pH, and desorption solvent and its volume, was investigated in detail. Under optimal conditions, the MSPE coupled with LC-MS/MS exhibited good linearity ranging from 0.5 to 100 mug L(-1) with correlation coefficients (R(2)) >/= 0.9919, high sensitivity with low limits of detection (LODs) of 0.005-0.141 mug L(-1) and satisfactory recoveries of 67.4-105.5% with relative standard deviations (RSDs) < 9.8%. These results indicate that this method is reliable for the determination of SUHs in different matrices and the in situ growth strategy is a promising approach for constructing effective adsorbents. Graphical abstract Schematic representation of a "half" core-shell magnetic nanohybrid composed of zeolitic imidazolate framework (ZIF-8) and graphitic carbon nitride (g-C(3)N(4)) for magnetic solid-phase extraction (MSPE) of trace level determination of fifteen sulfonylurea herbicides (SUHs) in environmental water samples using LC-MS/MS detection. FAU - Qi, Yan AU - Qi Y AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. AD - Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People's Republic of China. FAU - Wan, Mengfei AU - Wan M AD - College of Grain, Henan University of Technology, Zhengzhou, 450001, People's Republic of China. FAU - Abd El-Aty, A M AU - Abd El-Aty AM AD - Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt. AD - Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240, Erzurum, Turkey. FAU - Li, Hui AU - Li H AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. FAU - Cao, Liping AU - Cao L AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. FAU - She, Yongxin AU - She Y AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. FAU - Shao, Yong AU - Shao Y AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. FAU - Jin, Fen AU - Jin F AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. FAU - Wang, Shanshan AU - Wang S AUID- ORCID: 0000-0002-9289-8174 AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. wangshanshan@caas.cn. FAU - Wang, Jing AU - Wang J AUID- ORCID: 0000-0002-8961-9277 AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture, Beijing, 100081, People's Republic of China. w_jing2001@126.com. LA - eng GR - 2018YFC1603500/National Key Scientific Instrument and Equipment Development Projects of China (CN)/International GR - 2018BC005/National Key Research and Development Program of Yunnan Province/International GR - AA17204043-2/Guangxi Innovation-driven Development Project/International PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200420 PL - Austria TA - Mikrochim Acta JT - Mikrochimica acta JID - 7808782 SB - IM OTO - NOTNLM OT - Graphitic carbon nitride nanosheets OT - In situ growth OT - Magnetic solid-phase extraction OT - Sulfonylurea herbicides OT - Zeolitic imidazolate frameworks-8 EDAT- 2020/04/22 06:00 MHDA- 2020/04/22 06:01 CRDT- 2020/04/22 06:00 PHST- 2019/11/25 00:00 [received] PHST- 2020/03/30 00:00 [accepted] PHST- 2020/04/22 06:00 [entrez] PHST- 2020/04/22 06:00 [pubmed] PHST- 2020/04/22 06:01 [medline] AID - 10.1007/s00604-020-04243-5 [pii] AID - 10.1007/s00604-020-04243-5 [doi] PST - epublish SO - Mikrochim Acta. 2020 Apr 20;187(5):279. doi: 10.1007/s00604-020-04243-5.