PMID- 32316980
OWN - NLM
STAT- MEDLINE
DCOM- 20201013
LR  - 20201013
IS  - 1757-7241 (Electronic)
IS  - 1757-7241 (Linking)
VI  - 28
IP  - 1
DP  - 2020 Apr 21
TI  - Therapeutic management of severe hypothermia with veno-arterial ECMO: where do we 
      stand? Case report and review of the current literature.
PG  - 30
LID - 10.1186/s13049-020-00723-y [doi]
LID - 30
AB  - BACKGROUND: Severe accidental hypothermia is associated with high morbidity and 
      mortality. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides 
      an efficient rewarming method with complete cardiopulmonary support. The use of 
      VA-ECMO for this indication has greatly improved the vital and functional 
      prognosis of patients. CASE PRESENTATION: We report a case of a 46-year-old 
      patient who was treated for severe hypothermia with a temperature of 22.4  degrees C 
      along with initial cardiac arrest, whose progression was favorable after the 
      implementation of VA-ECMO support. Two months after initial cardiac arrest, the 
      patient was reassessed and showed signs of complete recovery with regard to his 
      mental and physical capacities. CONCLUSIONS: The recent international 
      publications and groups of experts recommend the use of VA ECMO as the gold 
      standard therapy to treat severe hypothermia. Therefore, it seems suitable to 
      update the current knowledge on the topic by analysing the latest international 
      publications. The performance of this technique calls into question ethical and 
      economic factors. Two distinct medical teams tried to identify and regroup 
      prognosis factors in predictive survival scores. They raise the question of the 
      utility of these scores in clinical practice. Indeed, according to which survival 
      rate should we proceed to prolonged resuscitation and implement VA-ECMO? 
      Additional studies will be needed for external approval of these survival scores, 
      and additional reflection by experts will be required.
FAU - Ledoux, Aurelien
AU  - Ledoux A
AD  - Department of Intensive Care Medicine, General Hospital of Valenciennes, 
      Valenciennes, France.
FAU - Saint Leger, Piehr
AU  - Saint Leger P
AD  - Department of Intensive Care Medicine, General Hospital of Valenciennes, 
      Valenciennes, France. saintleger-p@ch-valenciennes.fr.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20200421
PL  - England
TA  - Scand J Trauma Resusc Emerg Med
JT  - Scandinavian journal of trauma, resuscitation and emergency medicine
JID - 101477511
SB  - IM
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Heart Arrest/etiology/*therapy
MH  - Humans
MH  - Hypothermia/etiology/*therapy
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - *Resuscitation
MH  - Rewarming/*methods
PMC - PMC7175497
OTO - NOTNLM
OT  - Cardiac arrest
OT  - Extracorporeal membrane oxygenation
OT  - Hypothermia
OT  - Rewarming
COIS- The authors declare that they have no competing interests.
EDAT- 2020/04/23 06:00
MHDA- 2020/10/21 06:00
PMCR- 2020/04/21
CRDT- 2020/04/23 06:00
PHST- 2019/11/26 00:00 [received]
PHST- 2020/04/13 00:00 [accepted]
PHST- 2020/04/23 06:00 [entrez]
PHST- 2020/04/23 06:00 [pubmed]
PHST- 2020/10/21 06:00 [medline]
PHST- 2020/04/21 00:00 [pmc-release]
AID - 10.1186/s13049-020-00723-y [pii]
AID - 723 [pii]
AID - 10.1186/s13049-020-00723-y [doi]
PST - epublish
SO  - Scand J Trauma Resusc Emerg Med. 2020 Apr 21;28(1):30. doi: 
      10.1186/s13049-020-00723-y.