PMID- 32317224
OWN - NLM
STAT- MEDLINE
DCOM- 20220614
LR  - 20230502
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Print)
IS  - 0920-9964 (Linking)
VI  - 243
DP  - 2022 May
TI  - North American Prodrome Longitudinal Study (NAPLS 3): Methods and baseline 
      description.
PG  - 262-267
LID - S0920-9964(20)30217-6 [pii]
LID - 10.1016/j.schres.2020.04.010 [doi]
AB  - The North American Prodrome Longitudinal Study (NAPLS) is a consortium of nine 
      programs focusing on youth at clinical high risk (CHR) for psychosis. Funded by 
      the National Institute of Mental Health (NIMH), the sites are located at Emory 
      University, Harvard University, University of Calgary, University of California 
      at Los Angeles, at San Diego, and at San Francisco, University of North Carolina 
      Chapel Hill, Yale University, and Zucker Hillside Hospital. There have been two 
      previous endeavors completed by this consortium, known as NAPLS-1 and NAPLS-2. 
      This paper first offers an overview of the methodology of the third phase of the 
      NAPLS consortium, the second five-year prospective study NAPLS-3, which aims to 
      determine mechanisms of the development of psychosis. In addition, we report on 
      the ascertainment and demographics of the 710 CHR participants in NAPLS-3.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Addington, Jean
AU  - Addington J
AD  - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 
      Calgary, Alberta, Canada. Electronic address: jmadding@ucalgary.ca.
FAU - Liu, Lu
AU  - Liu L
AD  - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 
      Calgary, Alberta, Canada.
FAU - Brummitt, Kali
AU  - Brummitt K
AD  - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 
      Calgary, Alberta, Canada.
FAU - Bearden, Carrie E
AU  - Bearden CE
AD  - Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA, 
      United States of America.
FAU - Cadenhead, Kristin S
AU  - Cadenhead KS
AD  - Department of Psychiatry, UCSD, San Diego, CA, United States of America.
FAU - Cornblatt, Barbara A
AU  - Cornblatt BA
AD  - Department of Psychiatry, Zucker Hillside Hospital, Long Island, NY, United 
      States of America.
FAU - Keshavan, Matcheri
AU  - Keshavan M
AD  - Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical 
      Center and Massachusetts General Hospital, Boston, MA, United States of America.
FAU - Mathalon, Daniel H
AU  - Mathalon DH
AD  - Department of Psychiatry, UCSF, and SFVA Medical Center, San Francisco, CA, 
      United States of America.
FAU - McGlashan, Thomas H
AU  - McGlashan TH
AD  - Department of Psychiatry, Yale University, New Haven, CT, United States of 
      America.
FAU - Perkins, Diana O
AU  - Perkins DO
AD  - Department of Psychiatry, University of North Carolina, Chapel Hill, NC, United 
      States of America.
FAU - Seidman, Larry J
AU  - Seidman LJ
AD  - Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical 
      Center and Massachusetts General Hospital, Boston, MA, United States of America.
FAU - Stone, William
AU  - Stone W
AD  - Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical 
      Center and Massachusetts General Hospital, Boston, MA, United States of America.
FAU - Tsuang, Ming T
AU  - Tsuang MT
AD  - Department of Psychiatry, UCSD, San Diego, CA, United States of America; 
      Institute of Genomic Medicine, University of California, La Jolla, CA, United 
      States of America.
FAU - Walker, Elaine F
AU  - Walker EF
AD  - Departments of Psychology and Psychiatry, Emory University, Atlanta, GA, United 
      States of America.
FAU - Woods, Scott W
AU  - Woods SW
AD  - Department of Psychiatry, Yale University, New Haven, CT, United States of 
      America.
FAU - Cannon, Tyrone D
AU  - Cannon TD
AD  - Department of Psychology, Yale University, New Haven, CT, United States of 
      America.
LA  - eng
GR  - UL1 TR001863/TR/NCATS NIH HHS/United States
GR  - U01 MH081902/MH/NIMH NIH HHS/United States
GR  - U01 MH081988/MH/NIMH NIH HHS/United States
GR  - U01 MH076989/MH/NIMH NIH HHS/United States
GR  - U01 MH081928/MH/NIMH NIH HHS/United States
GR  - U01 MH082022/MH/NIMH NIH HHS/United States
GR  - U01 MH081984/MH/NIMH NIH HHS/United States
GR  - U01 MH081857/MH/NIMH NIH HHS/United States
GR  - U01 MH082004/MH/NIMH NIH HHS/United States
GR  - U01 MH081944/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
DEP - 20200418
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adolescent
MH  - Humans
MH  - Longitudinal Studies
MH  - North America/epidemiology
MH  - *Prodromal Symptoms
MH  - Prospective Studies
MH  - *Psychotic Disorders/epidemiology
PMC - PMC7572535
MID - NIHMS1587970
OTO - NOTNLM
OT  - Clinical high risk
OT  - Methodology
OT  - Psychosis
OT  - Schizophrenia
COIS- Conflict of Interest Authors declare they have no conflict of interest with 
      respect to this study.
EDAT- 2020/04/23 06:00
MHDA- 2022/06/15 06:00
PMCR- 2023/05/01
CRDT- 2020/04/23 06:00
PHST- 2019/07/24 00:00 [received]
PHST- 2020/02/10 00:00 [revised]
PHST- 2020/04/06 00:00 [accepted]
PHST- 2020/04/23 06:00 [pubmed]
PHST- 2022/06/15 06:00 [medline]
PHST- 2020/04/23 06:00 [entrez]
PHST- 2023/05/01 00:00 [pmc-release]
AID - S0920-9964(20)30217-6 [pii]
AID - 10.1016/j.schres.2020.04.010 [doi]
PST - ppublish
SO  - Schizophr Res. 2022 May;243:262-267. doi: 10.1016/j.schres.2020.04.010. Epub 2020 
      Apr 18.