PMID- 32322761
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220216
IS  - 2452-199X (Electronic)
IS  - 2452-199X (Linking)
VI  - 5
IP  - 3
DP  - 2020 Sep
TI  - Improving mechanical and antibacterial properties of PMMA via polyblend 
      electrospinning with silk fibroin and polyethyleneimine towards dental 
      applications.
PG  - 510-515
LID - 10.1016/j.bioactmat.2020.04.005 [doi]
AB  - Poly(methylmethacrylate) (PMMA) is a widely used material in dental applications, 
      particularly as denture resins. Due to thermally unstable and wet oral cavity, 
      the implanted PMMA based resins occasionally deform and grow bacterial biofilms 
      at the interface between oral cavity and the biomaterial. Several strategies 
      attempted earlier to improve the bacterial resistance and mechanical performance 
      of PMMA. Poly(ethyleneimine) (PEI) is a hyperbranched cationic polymer shown 
      earlier to improve antibacterial activity of resins but do not improve mechanical 
      properties of the resins alone, while silk fibroin (SF) is a natural biopolymer 
      with unique material properties. In this study, we combined SF and PEI towards 
      development of antibacterial and mechanically superior PMMA based materials 
      towards overcoming its drawbacks. Using polyblend electrospinning to combine SF, 
      PEI and PMMA, we successfully developed intrinsically antibacterial and 
      mechanically reinforced nanofiber mats. We propose that the resulting nanofiber 
      mats have the potential to be incorporated into PMMA based denture resin 
      materials to overcome the problems of patients and improve their quality of life.
CI  - (c) 2020 Production and hosting by Elsevier B.V. on behalf of KeAi Communications 
      Co., Ltd.
FAU - Karatepe, Ugur Yunus
AU  - Karatepe UY
AD  - Molecular Biology and Genetics Department, Tokat Gaziosmanpasa University, 
      Tasliciftlik, Tokat, Turkey.
FAU - Ozdemir, Tugba
AU  - Ozdemir T
AD  - Molecular Biology and Genetics Department, Tokat Gaziosmanpasa University, 
      Tasliciftlik, Tokat, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20200415
PL  - China
TA  - Bioact Mater
JT  - Bioactive materials
JID - 101685294
PMC - PMC7163214
OTO - NOTNLM
OT  - Bacterial resistance
OT  - Dental biomaterials
OT  - PEI
OT  - Reinforced
OT  - SF
COIS- None.
EDAT- 2020/04/24 06:00
MHDA- 2020/04/24 06:01
PMCR- 2020/04/15
CRDT- 2020/04/24 06:00
PHST- 2020/01/10 00:00 [received]
PHST- 2020/04/02 00:00 [revised]
PHST- 2020/04/05 00:00 [accepted]
PHST- 2020/04/24 06:00 [entrez]
PHST- 2020/04/24 06:00 [pubmed]
PHST- 2020/04/24 06:01 [medline]
PHST- 2020/04/15 00:00 [pmc-release]
AID - S2452-199X(20)30057-8 [pii]
AID - 10.1016/j.bioactmat.2020.04.005 [doi]
PST - epublish
SO  - Bioact Mater. 2020 Apr 15;5(3):510-515. doi: 10.1016/j.bioactmat.2020.04.005. 
      eCollection 2020 Sep.