PMID- 32334292 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240227 IS - 1873-4529 (Electronic) IS - 0952-8180 (Linking) VI - 64 DP - 2020 Apr 22 TI - The impact of fascia iliaca compartment block on chronic postsurgical pain in patients undergoing hip fracture repair. PG - 109801 LID - S0952-8180(19)31809-4 [pii] LID - 10.1016/j.jclinane.2020.109801 [doi] AB - STUDY OBJECTIVE: Chronic postsurgical pain (CPSP), i.e. pain persisting >3 months, may appear after any type of surgery. There is a paucity of literature addressing CPSP development after hip fracture repair and the impact of any analgesic intervention on the development of CPSP in patients after hip fracture surgery. This study is the first aiming to examine the impact of ultrasound-guided fascia iliaca compartment block (USG FICB) on the development of CPSP after hip fracture repair. DESIGN: Prospective randomized study. SETTING: Operating room. PATIENTS: 182 patients scheduled for hip fracture surgery. INTERVENTIONS: Patients were randomized to receive a USG FICB (FICB group) or a sham saline injection (sham FICB group), twenty minutes before positioning for spinal anesthesia. MEASUREMENTS: The hip - related characteristic pain intensity (CPI) at 3- months post-surgery was the primary outcome measure. Presence and severity of hip-related pain at 3- and 6-months post-surgery, numeric rating pain scale (NRS) scores at 6, 24, 36, 48 postoperative hours, total 24-hour tramadol PCA administration and timing of the first tramadol dose, were documented as well. MAIN RESULTS: FICB group presented with lower CPI scores 3- months postoperatively (p < 0.01), as well as lower percentage of patients with high-grade CPSP, 3 and 6 months postoperatively (p < 0.001). FICB group also showed significantly lower NRS scores in all instances, lower total 24 - hour tramadol consumption and higher mean time to first tramadol dose (p < 0.05). The overall sample of 182 patients reported a considerably high incidence of hip -related CPSP (60% at 3 months, 45% at 6 months). CONCLUSIONS: USG FICB in the perioperative setting may reduce the incidence, intensity and severity of CPSP at 3 and 6 months after hip fracture surgery, providing safe and effective postoperative analgesia. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Diakomi, Maria AU - Diakomi M AD - Department of Anesthesiology, Asklepieion Hospital of Voula, Athens, Greece. FAU - Papaioannou, Marianna AU - Papaioannou M AD - Department of Anesthesiology, Asklepieion Hospital of Voula, Athens, Greece. FAU - Georgoudis, George AU - Georgoudis G AD - Physiotherapy Department, University of West Attica, Athens, Greece. FAU - Argyra, Erifili AU - Argyra E AD - Department of Anesthesiology, Aretaieion University Hospital, Athens, Greece. FAU - Mela, Argyro AU - Mela A AD - Department of Anesthesiology, Asklepieion Hospital of Voula, Athens, Greece. FAU - Siafaka, Ioanna AU - Siafaka I AD - Department of Anesthesiology, Aretaieion University Hospital, Athens, Greece. FAU - Makris, Alexandros AU - Makris A AD - Department of Anesthesiology, Asklepieion Hospital of Voula, Athens, Greece. Electronic address: makrisalexandros@hotmail.com. LA - eng PT - Journal Article DEP - 20200422 PL - United States TA - J Clin Anesth JT - Journal of clinical anesthesia JID - 8812166 SB - IM OTO - NOTNLM OT - Acute pain OT - Chronic pain OT - Lower extremity COIS- Declaration of competing interest The authors declare no conflicts of interest and no sources of funding for this manuscript. EDAT- 2020/04/26 06:00 MHDA- 2020/04/26 06:01 CRDT- 2020/04/26 06:00 PHST- 2019/11/10 00:00 [received] PHST- 2020/02/12 00:00 [revised] PHST- 2020/04/04 00:00 [accepted] PHST- 2020/04/26 06:01 [medline] PHST- 2020/04/26 06:00 [pubmed] PHST- 2020/04/26 06:00 [entrez] AID - S0952-8180(19)31809-4 [pii] AID - 10.1016/j.jclinane.2020.109801 [doi] PST - aheadofprint SO - J Clin Anesth. 2020 Apr 22;64:109801. doi: 10.1016/j.jclinane.2020.109801.