PMID- 32349698
OWN - NLM
STAT- MEDLINE
DCOM- 20201109
LR  - 20240328
IS  - 1471-244X (Electronic)
IS  - 1471-244X (Linking)
VI  - 20
IP  - 1
DP  - 2020 Apr 29
TI  - Mindfulness-based crisis interventions (MBCI) for psychosis within acute 
      inpatient psychiatric settings; a feasibility randomised controlled trial.
PG  - 193
LID - 10.1186/s12888-020-02608-x [doi]
LID - 193
AB  - BACKGROUND: Inpatient psychiatric care is a scarce and expensive resource in the 
      National Health Service (NHS), with chronic bed shortages being partly driven by 
      high re-admission rates. Brief inpatient talking therapies for psychosis could 
      help reduce re-admission rates. The primary aim was to assess feasibility and 
      acceptability of a novel, brief, mindfulness-based intervention for inpatients 
      with psychosis. The secondary aim was to collect pilot outcome data on 
      readmission rate, at 6 and 12 months (m) post discharge, and self-report symptom 
      measures at 6 m. METHODS: The amBITION study (BrIef Talking therapIes ON wards) 
      was a parallel group, feasibility randomised controlled trial (RCT). In addition 
      to treatment as usual (TAU), eligible inpatients with psychotic symptoms were 
      randomly allocated to receive either (Mindfulness-Based Crisis Intervention; 
      MBCI) or a control intervention (Social Activity Therapy; SAT), for 1-5 sessions. 
      RESULTS: Fifty participants were recruited (26 MBCI; 24 SAT); all received at 
      least 1 therapy session (mean = 3). Follow-up rates were 98% at 6 m and 96% at 
      12 m for service use data extracted from clinical notes, and 86% for self-report 
      measures. At 6 m follow-up, re-admission rates were similar across groups 
      (MBCI = 6, SAT = 5; odds ratio = 1.20, 95% CI: 0.312-4.61). At 12 m follow-up, 
      re-admissions were lower in the MBCI group (MBCI = 7, SAT = 11; odds 
      ratio = 0.46, 95% CI: 0.14-1.51). Three participants experienced adverse events; 
      none was related to trial participation. CONCLUSIONS: Delivering a brief 
      mindfulness-based inpatient intervention for psychosis is feasible and 
      acceptable, and may reduce risk of short-term readmission. These promising 
      findings warrant progression to a larger clinical effectiveness trial. TRIAL 
      REGISTRATION: ISRCTN37625384.
FAU - Jacobsen, Pamela
AU  - Jacobsen P
AUID- ORCID: 0000-0001-8847-7775
AD  - Department of Psychology, King's College London, Institute of Psychiatry, 
      Psychology and Neuroscience (IoPPN), De Crespigny Park, London, SE5 8AF, UK. 
      pcj25@bath.ac.uk.
AD  - Department of Psychology, University of Bath, Bath, BA2 7AY, UK. 
      pcj25@bath.ac.uk.
FAU - Peters, Emmanuelle
AU  - Peters E
AD  - Department of Psychology, King's College London, Institute of Psychiatry, 
      Psychology and Neuroscience (IoPPN), De Crespigny Park, London, SE5 8AF, UK.
AD  - South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Monks 
      Orchard Road, Beckenham, Kent, BR3 3BX, UK.
FAU - Robinson, Emily J
AU  - Robinson EJ
AD  - Department of Biostatistics & Health Informatics, King's College London, 
      Institute of Psychiatry, Psychology and Neuroscience (IoPPN), De Crespigny Park, 
      London, SE5 8AF, UK.
AD  - Present address: School of Population Health and Environmental Sciences, King's 
      College London, London, SE1 1UL, UK.
FAU - Chadwick, Paul
AU  - Chadwick P
AD  - Department of Psychology, King's College London, Institute of Psychiatry, 
      Psychology and Neuroscience (IoPPN), De Crespigny Park, London, SE5 8AF, UK.
AD  - Department of Psychology, University of Bath, Bath, BA2 7AY, UK.
LA  - eng
GR  - DRF-2014-07-003/DH_/Department of Health/United Kingdom
GR  - DRF-2014-07-003/Research Trainees Coordinating Centre/International
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20200429
PL  - England
TA  - BMC Psychiatry
JT  - BMC psychiatry
JID - 100968559
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aftercare
MH  - Aged
MH  - *Crisis Intervention
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Inpatients/*psychology
MH  - Male
MH  - Middle Aged
MH  - *Mindfulness
MH  - Patient Discharge
MH  - Psychotic Disorders/*therapy
MH  - State Medicine
MH  - Young Adult
PMC - PMC7191699
OTO - NOTNLM
OT  - Crisis intervention
OT  - Mindfulness
OT  - Psychiatric hospital readmission
OT  - Psychiatric units
OT  - Psychosis
OT  - Psychotherapy
COIS- The authors declare that they have no competing interests.
EDAT- 2020/05/01 06:00
MHDA- 2020/11/11 06:00
PMCR- 2020/04/29
CRDT- 2020/05/01 06:00
PHST- 2019/10/21 00:00 [received]
PHST- 2020/04/19 00:00 [accepted]
PHST- 2020/05/01 06:00 [entrez]
PHST- 2020/05/01 06:00 [pubmed]
PHST- 2020/11/11 06:00 [medline]
PHST- 2020/04/29 00:00 [pmc-release]
AID - 10.1186/s12888-020-02608-x [pii]
AID - 2608 [pii]
AID - 10.1186/s12888-020-02608-x [doi]
PST - epublish
SO  - BMC Psychiatry. 2020 Apr 29;20(1):193. doi: 10.1186/s12888-020-02608-x.