PMID- 32350335
OWN - NLM
STAT- MEDLINE
DCOM- 20210106
LR  - 20210429
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 10
IP  - 1
DP  - 2020 Apr 29
TI  - Latitudinal drivers of oyster mortality: deciphering host, pathogen and 
      environmental risk factors.
PG  - 7264
LID - 10.1038/s41598-020-64086-1 [doi]
LID - 7264
AB  - Diseases pose an ongoing threat to aquaculture, fisheries and conservation of 
      marine species, and determination of risk factors of disease is crucial for 
      management. Our objective was to decipher the effects of host, pathogen and 
      environmental factors on disease-induced mortality of Pacific oysters 
      (Crassostrea gigas) across a latitudinal gradient. We deployed young and adult 
      oysters at 13 sites in France and we monitored survival, pathogens and 
      environmental parameters. The young oysters came from either the wild collection 
      or the hatchery while the adults were from the wild only. We then used Cox 
      regression models to investigate the effect of latitude, site, environmental 
      factors and origin on mortality risk and to extrapolate this mortality risk to 
      the distribution limits of the species in Europe. We found that seawater 
      temperature, food level, sea level atmospheric pressure, rainfall and wind speed 
      were associated with mortality risk. Their effect on hatchery oysters was 
      generally higher than on wild animals, probably reflecting that hatchery oysters 
      were free of Ostreid herpesvirus 1 (OsHV-1) whereas those from the wild were 
      asymptomatic carriers. The risk factors involved in young and adult oyster 
      mortalities were different, reflecting distinct diseases. Mortality risk 
      increases from 0 to 90% with decreasing latitude for young hatchery oysters, but 
      not for young wild oysters or adults. Mortality risk was higher in wild oysters 
      than in hatchery ones at latitude > 47.6 degrees N while this was the opposite at lower 
      latitude. Therefore, latitudinal gradient alters disease-induced mortality risk 
      but interacts with the initial health status of the host and the pathogen 
      involved. Practically, we suggest that mortality can be mitigated by using 
      hatchery oysters in north and wild collected oysters in the south.
FAU - Fleury, Elodie
AU  - Fleury E
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France. 
      elodie.fleury@ifremer.fr.
FAU - Barbier, Pierrick
AU  - Barbier P
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France.
FAU - Petton, Bruno
AU  - Petton B
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France.
FAU - Normand, Julien
AU  - Normand J
AD  - Ifremer, Laboratoire Environnement Ressources de Normandie, 14520, Port en 
      Bessin, France.
FAU - Thomas, Yoann
AU  - Thomas Y
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France.
FAU - Pouvreau, Stephane
AU  - Pouvreau S
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France.
FAU - Daigle, Gaetan
AU  - Daigle G
AD  - Departement de Mathematiques et Statistique, Universite Laval, Sainte-Foy, 
      Quebec, G1K 7P4, Canada.
FAU - Pernet, Fabrice
AU  - Pernet F
AD  - Univ Brest, Ifremer, CNRS, IRD, LEMAR, F-29280, Plouzane, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200429
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Animals
MH  - Aquaculture
MH  - Disease Outbreaks
MH  - *Environment
MH  - *Host-Pathogen Interactions
MH  - *Ostreidae/microbiology
MH  - Proportional Hazards Models
MH  - Risk Factors
PMC - PMC7190702
COIS- The authors declare no competing interests.
EDAT- 2020/05/01 06:00
MHDA- 2021/01/07 06:00
PMCR- 2020/04/29
CRDT- 2020/05/01 06:00
PHST- 2020/01/09 00:00 [received]
PHST- 2020/04/04 00:00 [accepted]
PHST- 2020/05/01 06:00 [entrez]
PHST- 2020/05/01 06:00 [pubmed]
PHST- 2021/01/07 06:00 [medline]
PHST- 2020/04/29 00:00 [pmc-release]
AID - 10.1038/s41598-020-64086-1 [pii]
AID - 64086 [pii]
AID - 10.1038/s41598-020-64086-1 [doi]
PST - epublish
SO  - Sci Rep. 2020 Apr 29;10(1):7264. doi: 10.1038/s41598-020-64086-1.