PMID- 32350489
OWN - NLM
STAT- MEDLINE
DCOM- 20210331
LR  - 20210331
IS  - 2050-7518 (Electronic)
IS  - 2050-750X (Linking)
VI  - 8
IP  - 31
DP  - 2020 Aug 21
TI  - Functional peptide-based drug delivery systems.
PG  - 6517-6529
LID - 10.1039/d0tb00713g [doi]
AB  - Peptides are one of the most important functional motifs for constructing smart 
      drug delivery systems (DDSs). Functional peptides can be conjugated with drugs or 
      carriers via covalent bonds, or assembled into DDSs via supramolecular forces, 
      which enables the DDSs to acquire desired functions such as targeting and/or 
      environmental responsiveness. In this mini review, we first introduce the 
      different types of functional peptides that are commonly used for constructing 
      DDSs, and we highlight representative strategies for designing smart DDSs by 
      using functional peptides in the past few years. We also state the challenges of 
      peptide-based DDSs and come up with prospects.
FAU - Lian, Zheng
AU  - Lian Z
AD  - People's Public Security University of China, Beijing 100038, China.
FAU - Ji, Tianjiao
AU  - Ji T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20200430
PL  - England
TA  - J Mater Chem B
JT  - Journal of materials chemistry. B
JID - 101598493
RN  - 0 (Drug Carriers)
RN  - 0 (Peptides)
SB  - IM
MH  - Animals
MH  - Drug Carriers/*chemistry/metabolism
MH  - Drug Design
MH  - Humans
MH  - Peptides/*chemistry/metabolism
EDAT- 2020/05/01 06:00
MHDA- 2021/04/01 06:00
CRDT- 2020/05/01 06:00
PHST- 2020/05/01 06:00 [pubmed]
PHST- 2021/04/01 06:00 [medline]
PHST- 2020/05/01 06:00 [entrez]
AID - 10.1039/d0tb00713g [doi]
PST - ppublish
SO  - J Mater Chem B. 2020 Aug 21;8(31):6517-6529. doi: 10.1039/d0tb00713g. Epub 2020 
      Apr 30.