PMID- 32355875
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 8
IP  - 5
DP  - 2020 May
TI  - Endoscopic closure of refractory esophageal fistula after esophagectomy using 
      polyglycolic acid sheets: a pilot study.
PG  - E591-E595
LID - 10.1055/a-1119-6352 [doi]
AB  - Background and study aims  Esophageal fistulas after esophagectomy are associated 
      with high mortality and poor quality of life. They are sometimes intractable to 
      conservative management and surgery that increases mortality. Few studies have 
      assessed use of polyglycolic acid (PGA) sheets with fibrin glue for esophageal 
      fistulas. We investigated the safety of using PGA sheets with fibrin glue for 
      esophageal fistulas after esophagectomy. Patients and methods  This was a 
      single-center prospective pilot study. Patients who had refractory esophageal 
      fistulas after esophagectomy were included. PGA sheets were filled in the fistula 
      using biopsy forceps. Fibrin glue was applied to the PGA sheets. We repeated the 
      procedure 1 week later. The outcome measures were the incidence of adverse events 
      (AEs) and closure of the fistula. Results  Five patients were assessed. No 
      adverse events were observed. The esophageal fistula was closed with the 
      application of PGA sheets four times in 40 % (2/5) of the cases. Conclusions  PGA 
      sheets with fibrin glue were safe for esophageal fistula closure after 
      esophagectomy and do not involve the risk of AEs.
FAU - Nagami, Yasuaki
AU  - Nagami Y
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Ominami, Masaki
AU  - Ominami M
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Sakai, Taishi
AU  - Sakai T
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
AD  - Department of Gastroenterology, Baba Memorial Hospital 4-244, Nishiku Hamadera 
      Funao-Town-Higashi, Sakai-City, Japan.
FAU - Fukunaga, Shusei
AU  - Fukunaga S
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Tanaka, Fumio
AU  - Tanaka F
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Taira, Koichi
AU  - Taira K
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Tanigawa, Tetsuya
AU  - Tanigawa T
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Lee, Shigeru
AU  - Lee S
AD  - Department of Gastroenterological Surgery, Osaka City University Graduate School 
      of Medicine, Osaka, Japan.
FAU - Watanabe, Toshio
AU  - Watanabe T
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Fujiwara, Yasuhiro
AU  - Fujiwara Y
AD  - Department of Gastroenterology, Osaka City University Graduate School of 
      Medicine, Osaka, Japan.
LA  - eng
PT  - Journal Article
DEP - 20200417
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
CIN - Endosc Int Open. 2020 May;8(5):E596-E597. PMID: 32356851
PMC - PMC7165005
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2020/05/02 06:00
MHDA- 2020/05/02 06:01
PMCR- 2020/05/01
CRDT- 2020/05/02 06:00
PHST- 2019/07/30 00:00 [received]
PHST- 2019/01/23 00:00 [accepted]
PHST- 2020/05/02 06:00 [entrez]
PHST- 2020/05/02 06:00 [pubmed]
PHST- 2020/05/02 06:01 [medline]
PHST- 2020/05/01 00:00 [pmc-release]
AID - 10.1055/a-1119-6352 [doi]
PST - ppublish
SO  - Endosc Int Open. 2020 May;8(5):E591-E595. doi: 10.1055/a-1119-6352. Epub 2020 Apr 
      17.