PMID- 32356278
OWN - NLM
STAT- MEDLINE
DCOM- 20200929
LR  - 20200929
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 29
IP  - 9
DP  - 2020 Sep
TI  - Patient-reported outcomes in maintenance hemodialysis: a cross-sectional, 
      multicenter study.
PG  - 2345-2354
LID - 10.1007/s11136-020-02508-3 [doi]
AB  - PURPOSE: The aim of this study is to assess patient-reported outcome measures 
      (PROMs) related to symptoms among maintenance hemodialysis patients (MHDp). 
      METHODS: This cross-sectional study was conducted between 2013 and 2015, with 336 
      MHDp from five hospital hemodialysis units. It included a comprehensive 
      assessment of the prevalence and intensity of 30 common dialysis-related symptoms 
      quality of life and daily function of MHDp, by using the Dialysis Symptom Index 
      (DSI), Quality of Life Short Form (KDQOL-SF), and demographic and clinical 
      characteristics. RESULTS: The five most commonly reported symptoms were 
      identified as tiredness (80%), difficulty becoming sexually aroused (72%), 
      decreased interest in sex (72%), worrying (67%), trouble staying asleep (65%), 
      and trouble falling asleep (64%). Based on the DSI, the mean Overall Burden of 
      Symptoms (OBS), on a scale of 0-30, was 15.4 +/- 6.7, while the mean Overall 
      Symptom Severity Score (OSSS), on a scale of 0-150, was 54.8 +/- 29.8. Multivariate 
      quantile regression models indicated that major depression is consistently 
      associated with both the OBS and OSSS across different quantiles, whereas time on 
      dialysis > 24 months was associated with the OBS only. Both the OBS and OSSS were 
      inversely associated with KDQOL-SF: the kidney-related (KDCS), physical (PCS) and 
      mental aspects (MCS), across multiple quantiles in multivariate quantile 
      regression models. CONCLUSIONS: MHDp bear a heavy burden of symptom which are 
      associated with time spent on dialysis as well as depression. Clinical and 
      research resources should be directed at controlling symptoms, improving daily 
      function, detecting depression, and bettering quality of life.
FAU - Fleishman, Tatiana Talya
AU  - Fleishman TT
AD  - Division of Health in the Community, Ben-Gurion University of the Negev, 
      Beer-Sheva, Israel. talya.fleishman@MOH.GOV.IL.
AD  - Medical Affairs, Division of General Medicine, Ministry of Health, Jerusalem, 
      Israel. talya.fleishman@MOH.GOV.IL.
FAU - Dreiher, Jacob
AU  - Dreiher J
AD  - Division of Health in the Community, Ben-Gurion University of the Negev, 
      Beer-Sheva, Israel.
AD  - Soroka University Medical Center, Beer Sheva, Israel.
FAU - Shvartzman, Pesach
AU  - Shvartzman P
AD  - Division of Health in the Community, Ben-Gurion University of the Negev, 
      Beer-Sheva, Israel.
AD  - Soroka University Medical Center, Beer Sheva, Israel.
AD  - Southern District, Clalit Health Services, Beer Sheva, Israel.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20200430
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Adult
MH  - Aged
MH  - Anxiety/psychology
MH  - Cross-Sectional Studies
MH  - Fatigue/psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Patient Reported Outcome Measures
MH  - Prevalence
MH  - Psychometrics/methods
MH  - Quality of Life/*psychology
MH  - Renal Dialysis/*psychology
OTO - NOTNLM
OT  - Cross-sectional study
OT  - Maintenance hemodialysis
OT  - Palliative care
OT  - Patient-reported outcomes
OT  - Symptoms
EDAT- 2020/05/02 06:00
MHDA- 2020/09/30 06:00
CRDT- 2020/05/02 06:00
PHST- 2020/04/16 00:00 [accepted]
PHST- 2020/05/02 06:00 [pubmed]
PHST- 2020/09/30 06:00 [medline]
PHST- 2020/05/02 06:00 [entrez]
AID - 10.1007/s11136-020-02508-3 [pii]
AID - 10.1007/s11136-020-02508-3 [doi]
PST - ppublish
SO  - Qual Life Res. 2020 Sep;29(9):2345-2354. doi: 10.1007/s11136-020-02508-3. Epub 
      2020 Apr 30.