PMID- 32358415
OWN - NLM
STAT- MEDLINE
DCOM- 20210728
LR  - 20221005
IS  - 1873-4502 (Electronic)
IS  - 0886-3350 (Print)
IS  - 0886-3350 (Linking)
VI  - 46
IP  - 8
DP  - 2020 Aug
TI  - Innovative trifocal (quadrifocal) presbyopia-correcting IOLs: 1-year outcomes 
      from an international multicenter study.
PG  - 1142-1148
LID - 10.1097/j.jcrs.0000000000000232 [doi]
AB  - PURPOSE: To evaluate visual acuity (VA) and safety of the new AcrySof IQ PanOptix 
      presbyopia-correcting IOL at 12 months postimplantation. SETTING: Seventeen sites 
      in Europe, Australia, and South America. DESIGN: Prospective, single-arm, 
      nonmasked, nonrandomized study. METHODS: Of 167 patients enrolled, 149 received 
      study IOLs in both eyes; 145 completed the study. Binocular uncorrected distance 
      VA (UDVA; 4 m), monocular corrected distance VA (CDVA), binocular 
      distance-corrected intermediate VA (DCIVA; 60 cm and 80 cm), binocular 
      uncorrected near VA (UNVA; 40 cm), and binocular defocus curves were evaluated. 
      Safety was assessed by monitoring adverse events (AEs). RESULTS: Of 149 patients, 
      92 patients (62%) were women and 139 patients (93%) were white; mean +/- SD age was 
      68.9 +/- 9.3 years. At 12 months, mean binocular UDVA was 0.02 +/- 0.11 logarithm of 
      the minimum angle of resolution (logMAR); monocular CDVA was 0.01 +/- 0.13 logMAR 
      (first eye) and 0.01 +/- 0.10 logMAR (second eye); binocular DCIVA was 0.04 +/- 0.12 
      logMAR and 0.08 +/- 0.14 logMAR at 60 cm and 80 cm, respectively; and binocular 
      UNVA was 0.07 +/- 0.11 logMAR. At 6 months, mean binocular defocus curve VA (0.00 
      diopter [D] to -3.00 D) ranged from -0.04 to 0.13 logMAR. Binocular VA at 
      distance (0.00 D), intermediate (-1.50 D), and near (-2.50 D) was -0.04 +/- 0.11 
      logMAR, 0.07 +/- 0.13 logMAR, and 0.07 +/- 0.13 logMAR, respectively. Serious ocular 
      AE rates were 1.4% or less in first and second eyes. Posterior capsulotomy rates 
      were 3.4% (first eye) and 2.7% (second eye). CONCLUSIONS: The study IOL provided 
      good VA outcomes. Defocus curve showed VA of 20/25 Snellen or better from near to 
      intermediate distance. Rates of serious and nonserious AEs were low.
FAU - Kohnen, Thomas
AU  - Kohnen T
AD  - From the Department of Ophthalmology, Goethe-University (Kohnen), Frankfurt, 
      Germany; Eye Clinic, Department of Neurosciences, Biomedicine and Movement, 
      University of Verona, AOUI-Borgo Roma Hospital (Marchini), Verona, Italy; 
      Fernandez-Vega Ophthalmological Institute, School of Medicine, University of 
      Oviedo (Alfonso), Oviedo, Spain; Department of Ophthalmology, Macquare University 
      (Bala), Sydney, NSW, Australia; Ophthalmology Department, University Hospital CHU 
      (Cochener), Brest, France; Alcon Vision LLC (Martinez), Fort Worth, Texas, USA; 
      Centro Oftalmologico Carreno (Carreno), Santiago, Chile.
FAU - Marchini, Giorgio
AU  - Marchini G
FAU - Alfonso, Jose F
AU  - Alfonso JF
FAU - Bala, Chandra
AU  - Bala C
FAU - Cochener, Beatrice
AU  - Cochener B
FAU - Martinez, Aldo
AU  - Martinez A
FAU - Carreno, Edgardo
AU  - Carreno E
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - United States
TA  - J Cataract Refract Surg
JT  - Journal of cataract and refractive surgery
JID - 8604171
SB  - IM
MH  - Aged
MH  - Australia
MH  - Europe
MH  - Female
MH  - Humans
MH  - *Lenses, Intraocular
MH  - Middle Aged
MH  - *Phacoemulsification
MH  - *Presbyopia/surgery
MH  - Prospective Studies
MH  - Prosthesis Design
MH  - Pseudophakia
MH  - Refraction, Ocular
MH  - Vision, Binocular
PMC - PMC7688079
EDAT- 2020/05/03 06:00
MHDA- 2021/07/29 06:00
PMCR- 2020/11/25
CRDT- 2020/05/03 06:00
PHST- 2020/05/03 06:00 [pubmed]
PHST- 2021/07/29 06:00 [medline]
PHST- 2020/05/03 06:00 [entrez]
PHST- 2020/11/25 00:00 [pmc-release]
AID - 02158034-202008000-00013 [pii]
AID - JCRS-19-1097 [pii]
AID - 10.1097/j.jcrs.0000000000000232 [doi]
PST - ppublish
SO  - J Cataract Refract Surg. 2020 Aug;46(8):1142-1148. doi: 
      10.1097/j.jcrs.0000000000000232.