PMID- 32361472
OWN - NLM
STAT- MEDLINE
DCOM- 20210504
LR  - 20210504
IS  - 1873-264X (Electronic)
IS  - 0731-7085 (Linking)
VI  - 186
DP  - 2020 Jul 15
TI  - Systematic identification metabolites of Hemerocallis citrina Borani by 
      high-performance liquid chromatography/quadrupole-time-of-flight mass 
      spectrometry combined with a screening method.
PG  - 113314
LID - S0731-7085(20)30550-1 [pii]
LID - 10.1016/j.jpba.2020.113314 [doi]
AB  - Hemerocallis citrina Borani is an important crop and its flower buds are widely 
      consumed in East Asian areas as a vegetable, as well as in traditional Chinese 
      medicine, due to its health-promoting properties. Metabolites present in 
      plant-derived foods or medicines are in part responsible for their desirable 
      flavor profiles and health benefits. Nevertheless, detailed information about 
      these compounds in H. citrina is scarce. Therefore, this study aimed to 
      investigate the metabolites by high-performance liquid chromatography/quadrupole 
      time-of-flight mass spectrometry (HPLC-Q-TOF-MS). In this study, a total of 144 
      compounds, including 14 amides, 25 polyphenols, 44 flavonols, 35 anthraquinones, 
      15 naphthols, and 11 other components, were detected by the established screening 
      method and were identified by their precise m/z values, characteristic tandem 
      mass spectrometry (MS/MS) data and fragmentation pathways of references, 111 of 
      which were reported in this plant for the first time. The distribution of 
      identified ingredients in different parts of H. citrina was determined. 
      Interestingly, colchicine, which had been reported as a toxic compound in the 
      fresh flower buds in previous studies and various news reports, was not found. 
      This work marks the first comprehensive study of metabolites from commercial 
      flower buds and different parts of H. citrina.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Liu, Jinghong
AU  - Liu J
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - Zhong, Xiaohong
AU  - Zhong X
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - Jiang, Yingying
AU  - Jiang Y
AD  - College of Food Science and Technology, Hunan Agricultural University, Changsha, 
      410128, China.
FAU - Yu, Liuyi
AU  - Yu L
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - Huang, Xiuqiong
AU  - Huang X
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - Dong, Zhuang
AU  - Dong Z
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - Yang, Shuaiyong
AU  - Yang S
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
FAU - He, Wei
AU  - He W
AD  - Green Melody Bio-engineering Group Company Limited, Changsha 410329, China.
FAU - Zeng, Jianguo
AU  - Zeng J
AD  - College of Horticulture, Hunan Agricultural University, Changsha, 410128, China. 
      Electronic address: zengjianguo@hunau.edu.cn.
FAU - Qing, Zhixing
AU  - Qing Z
AD  - College of Food Science and Technology, Hunan Agricultural University, Changsha, 
      410128, China. Electronic address: qingzhixing@hunau.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20200420
PL  - England
TA  - J Pharm Biomed Anal
JT  - Journal of pharmaceutical and biomedical analysis
JID - 8309336
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Hemerocallis/*chemistry
MH  - Mass Spectrometry/methods
MH  - Plant Extracts/*analysis/chemistry/metabolism
OTO - NOTNLM
OT  - Colchicine
OT  - Hemerocallis citrina Borani
OT  - LC-MS
OT  - Metabolites
OT  - Screening method
COIS- Declaration of Competing Interest The authors declare that there are no conflicts 
      of interest.
EDAT- 2020/05/04 06:00
MHDA- 2021/05/05 06:00
CRDT- 2020/05/04 06:00
PHST- 2020/02/29 00:00 [received]
PHST- 2020/03/30 00:00 [revised]
PHST- 2020/04/11 00:00 [accepted]
PHST- 2020/05/04 06:00 [pubmed]
PHST- 2021/05/05 06:00 [medline]
PHST- 2020/05/04 06:00 [entrez]
AID - S0731-7085(20)30550-1 [pii]
AID - 10.1016/j.jpba.2020.113314 [doi]
PST - ppublish
SO  - J Pharm Biomed Anal. 2020 Jul 15;186:113314. doi: 10.1016/j.jpba.2020.113314. 
      Epub 2020 Apr 20.