PMID- 32363088
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220414
IS  - 2156-7514 (Print)
IS  - 2156-5597 (Electronic)
IS  - 2156-5597 (Linking)
VI  - 10
DP  - 2020
TI  - Quantification of Cardiac Output with Phase Contrast Magnetic Resonance Imaging 
      in Patients with Pulmonary Hypertension.
PG  - 26
LID - 10.25259/JCIS_36_2020 [doi]
LID - 26
AB  - OBJECTIVE: The purpose of the study is to compare phase contrast (PC) imaging 
      with invasive measurements of cardiac output (CO) in patients with pulmonary 
      hypertension (PH). MATERIALS AND METHODS: We analyzed 81 cases with PH who 
      underwent cardiac magnetic resonance imaging and right heart catheterization 
      (RHC). Measurement of CO and stroke volume (SV) by cardiac magnetic resonance 
      (CMR) was performed by PC imaging of the proximal aorta (Ao) and pulmonary artery 
      (Pa) and by RHC using the Fick and thermodilution (TD) methods. RESULTS: There 
      was good correlation in CO measurements between PC and RHC; however, there was 
      better correlation with SV measurements; Fick-TD (r=0.85), PC-TD (Ao r=0.77, Pa 
      r=0.79), and PC-Fick (Ao r = 0.73, Pa r = 0.78). Bland-Altman analysis of SV 
      showed that Pa PC had slightly lower standard deviation than Ao PC; PC-Fick (Pa 
      SD = 15.11 vs. Ao SD = 16.4 ml) and PC-TD (Pa SD = 16.99 ml vs. Ao SD = 17.4 ml) 
      while Fick-TD had the lowest (SD = 14.4 ml). Compared to Fick, measurement of SV 
      with Ao PC (‒4.12 ml) and Pa PC (0.22 ml) both had lower mean difference than TD 
      (‒11.1 ml). CONCLUSION: Non-invasive measurement of CO and SV using PC-CMR 
      correlates well with invasive measurement using RHC. Our study showed that PC-CMR 
      had high accuracy and precision when compared to Fick. Among all the modalities, 
      PC-CMR contributed the least amount of variation in measurements.
CI  - (c) 2020 Published by Scientific Scholar on behalf of Journal of Clinical Imaging 
      Science.
FAU - Po, Jose Ricardo
AU  - Po JR
AD  - Borgess Heart Institute, Ascension Borgess Hospital, 1722 Shaffer St., Kalamazoo, 
      Michigan, United States.
FAU - Tong, Matthew
AU  - Tong M
AD  - Department of Cardiovascular Medicine, Wexner Medical Center, 410 W 10th Ave, 
      Columbus, Ohio, United States.
FAU - Meeran, Talha
AU  - Meeran T
AD  - Department of Cardiology, Fortis Hospital Mulund, Mumbai, Maharashtra, India.
FAU - Potluri, Alekhya
AU  - Potluri A
AD  - Department of Cardiology, Einstein Medical Center, 5401 Old York Road, 
      Philadelphia, United States.
FAU - Raina, Amresh
AU  - Raina A
AD  - Cardiovascular Institute, Allegheny General Hospital, 320 E North Ave., 
      Pittsburgh, Pennsylvania, United States.
FAU - Doyle, Mark
AU  - Doyle M
AD  - Cardiovascular Institute, Allegheny General Hospital, 320 E North Ave., 
      Pittsburgh, Pennsylvania, United States.
FAU - Biederman, Robert
AU  - Biederman R
AD  - Cardiovascular Institute, Allegheny General Hospital, 320 E North Ave., 
      Pittsburgh, Pennsylvania, United States.
LA  - eng
PT  - Journal Article
DEP - 20200502
PL  - United States
TA  - J Clin Imaging Sci
JT  - Journal of clinical imaging science
JID - 101564708
PMC - PMC7193209
OTO - NOTNLM
OT  - Cardiac magnetic resonance imaging
OT  - Cardiac output
OT  - Phase contrast imaging
OT  - Pulmonary hypertension
OT  - Stroke volume
COIS- Robert Biederman, MD Honoraria: Amgen, Bracco, Lantheus, Sanofi/ RegeneronGrants: 
      Biotronik, NIH/NHLB, United Therapeutics. Amresh Raina, MD Consultant: 
      AbbotClinical trials: Actelion, Bayer, Bellerophon, United Therapeutics
EDAT- 2020/05/05 06:00
MHDA- 2020/05/05 06:01
PMCR- 2020/05/02
CRDT- 2020/05/05 06:00
PHST- 2020/03/16 00:00 [received]
PHST- 2020/04/13 00:00 [accepted]
PHST- 2020/05/05 06:00 [entrez]
PHST- 2020/05/05 06:00 [pubmed]
PHST- 2020/05/05 06:01 [medline]
PHST- 2020/05/02 00:00 [pmc-release]
AID - JCIS-10-26 [pii]
AID - 10.25259/JCIS_36_2020 [doi]
PST - epublish
SO  - J Clin Imaging Sci. 2020 May 2;10:26. doi: 10.25259/JCIS_36_2020. eCollection 
      2020.