PMID- 32371364 OWN - NLM STAT- MEDLINE DCOM- 20210621 LR - 20210621 IS - 1876-2026 (Electronic) IS - 1876-2018 (Linking) VI - 52 DP - 2020 Aug TI - Predicting factors for non-suicidal self-injury in patients with schizophrenia spectrum disorders and the role of substance use. PG - 102068 LID - S1876-2018(20)30179-9 [pii] LID - 10.1016/j.ajp.2020.102068 [doi] AB - Non-suicidal self-injury (NSSI) has been shown as a characteristic feature in many clinical populations in recent years and schizophrenia is one of the most common psychiatric disorders which is associated with NSSI. In this study, we aimed to investigate predictors of NSSI in patients with schizophrenia spectrum disorders (SSD) and the role of lifetime substance use disorder (SUD). A sample of 165 patients with a diagnosis of SSD who were in remission participated in the study. Lifetime NSSI was assessed using the Inventory of Statements About Self-injury (ISAS). Lifetime SUD were evaluated. Logistic regression analysis was conducted to predict NSSI. SUD was found to be related to NSSI in patients with SSD, and it was associated with an approximately fourfold increase in the risk of NSSI. The rates of lifetime SUD in our sample and in the NSSI (+) group were 38.2 % and 55.6 %, respectively. The most commonly abused substances among patients with NSSI were cannabis and synthetic cannabinoids. The prevalence of NSSI was 43.6 % in our sample. 'Self-cutting' was the most common type and 'affect regulation' was the most common function of NSSI. One of the most significant risk factors for NSSI was a previous history of suicide attempts. SUD appears to be a significant predictor of NSSI in patients with SSD. Further investigation of treatable risk factors such as SUD which are related to NSSI is needed. It is also essential to screen SSD patients for NSSI due to the probable relation to high risk of suicide. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Guney, Erengul AU - Guney E AD - Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry and Neurology, Bakirkoy, Istanbul, 34280, Turkey. Electronic address: erenguney@outlook.com. FAU - Alniak, Izgi AU - Alniak I AD - Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry and Neurology, Bakirkoy, Istanbul, 34280, Turkey. FAU - Erkiran, Murat AU - Erkiran M AD - Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry and Neurology, Bakirkoy, Istanbul, 34280, Turkey. LA - eng PT - Journal Article DEP - 20200421 PL - Netherlands TA - Asian J Psychiatr JT - Asian journal of psychiatry JID - 101517820 SB - IM MH - Humans MH - Risk Factors MH - *Schizophrenia/epidemiology MH - *Self-Injurious Behavior/epidemiology MH - *Substance-Related Disorders/epidemiology MH - Suicidal Ideation MH - Suicide, Attempted OTO - NOTNLM OT - Non-suicidal self-injury OT - Schizophrenia spectrum disorders OT - Substance use disorder EDAT- 2020/05/07 06:00 MHDA- 2021/06/22 06:00 CRDT- 2020/05/07 06:00 PHST- 2019/12/09 00:00 [received] PHST- 2020/03/31 00:00 [revised] PHST- 2020/04/01 00:00 [accepted] PHST- 2020/05/07 06:00 [pubmed] PHST- 2021/06/22 06:00 [medline] PHST- 2020/05/07 06:00 [entrez] AID - S1876-2018(20)30179-9 [pii] AID - 10.1016/j.ajp.2020.102068 [doi] PST - ppublish SO - Asian J Psychiatr. 2020 Aug;52:102068. doi: 10.1016/j.ajp.2020.102068. Epub 2020 Apr 21.