PMID- 32378893 OWN - NLM STAT- MEDLINE DCOM- 20210108 LR - 20210108 IS - 1520-5118 (Electronic) IS - 0021-8561 (Linking) VI - 68 IP - 22 DP - 2020 Jun 3 TI - Polyhalogenated Compounds (Halogenated Natural Products and POPs) in Sardine (Sardinops sagax) from the South Atlantic and Indian Oceans. PG - 6084-6091 LID - 10.1021/acs.jafc.0c01530 [doi] AB - Halogenated natural products (HNPs) and persistent organic pollutants (POPs) were quantified in South African sardines (Sardinops sagax) from one site in the South Atlantic Ocean and one in the Indian Ocean. At both sites, HNPs [2,3,3',4,4',5,5'-heptachloro-1'-methyl-1,2'-bipyrrole (Q1), mixed halogenated compound 1 (MHC-1), 2,4,6-tribromoanisole (2,4,6-TBA), 2'-MeO-BDE 68 (BC-2), and 6-MeO-BDE 47 (BC-3)] were 1 order of magnitude higher concentrated than anthropogenic POPs [mainly polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), approximately 3 ng/g lipids]. MHC-1 and Q1 were the major HNPs in the samples from both sites, contributing with up to 49 and 52 ng/g lipids, respectively. The same 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (p,p'-DDE)/PCB ratio suggested that the major POPs were evenly distributed at both sites. Different ratios of Q1/MHC-1 in the samples from the Indian ( approximately 2:1) and South Atlantic ( approximately 1:1) Oceans indicated that the occurrence of HNPs in seafood is difficult to predict and should be investigated more in detail. The PCB levels in sardines were found to pose no risk to human consumers, whereas HNPs could not be evaluated because of the lack of toxicological data. FAU - Wu, Qiong AU - Wu Q AUID- ORCID: 0000-0003-1420-4023 AD - Institute of Food Chemistry (170b), University of Hohenheim, Garbenstrasse 28, D-70599 Stuttgart, Germany. FAU - Schlag, Sarah AU - Schlag S AD - Institute of Food Chemistry (170b), University of Hohenheim, Garbenstrasse 28, D-70599 Stuttgart, Germany. FAU - Uren, Ryan AU - Uren R AD - Environmental Sciences and Management, North-West University, 2531 Potchefstroom, South Africa. FAU - van der Lingen, Carl D AU - van der Lingen CD AD - Fisheries Management, Department of Agriculture, Forestry and Fisheries, 8000 Cape Town, South Africa. AD - Marine Research Institute and Department of Biological Sciences, University of Cape Town, 7701 Cape Town, South Africa. FAU - Bouwman, Hindrik AU - Bouwman H AD - Environmental Sciences and Management, North-West University, 2531 Potchefstroom, South Africa. FAU - Vetter, Walter AU - Vetter W AUID- ORCID: 0000-0002-5592-4265 AD - Institute of Food Chemistry (170b), University of Hohenheim, Garbenstrasse 28, D-70599 Stuttgart, Germany. LA - eng PT - Journal Article DEP - 20200521 PL - United States TA - J Agric Food Chem JT - Journal of agricultural and food chemistry JID - 0374755 RN - 0 (Hydrocarbons, Halogenated) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Animals MH - Atlantic Ocean MH - Fishes/*metabolism MH - Food Contamination/*analysis MH - Hydrocarbons, Halogenated/*analysis/metabolism MH - Indian Ocean MH - Seafood/*analysis MH - Water Pollutants, Chemical/*analysis/metabolism OTO - NOTNLM OT - South Africa OT - halogenated natural product OT - naturally produced organohalogen OT - persistent organic pollutant OT - polychlorinated biphenyl OT - sardine EDAT- 2020/05/08 06:00 MHDA- 2021/01/09 06:00 CRDT- 2020/05/08 06:00 PHST- 2020/05/08 06:00 [pubmed] PHST- 2021/01/09 06:00 [medline] PHST- 2020/05/08 06:00 [entrez] AID - 10.1021/acs.jafc.0c01530 [doi] PST - ppublish SO - J Agric Food Chem. 2020 Jun 3;68(22):6084-6091. doi: 10.1021/acs.jafc.0c01530. Epub 2020 May 21.