PMID- 32381079
OWN - NLM
STAT- MEDLINE
DCOM- 20210201
LR  - 20210201
IS  - 1471-2474 (Electronic)
IS  - 1471-2474 (Linking)
VI  - 21
IP  - 1
DP  - 2020 May 7
TI  - Synovial sarcoma presenting as an intra-articular mass in a pediatric patient: a 
      case report.
PG  - 283
LID - 10.1186/s12891-020-03312-3 [doi]
LID - 283
AB  - BACKGROUND: Synovial sarcoma (SS) is one of the reported sarcomas in the 
      pediatric and adult populations. Delay in diagnosis and treatment is common in SS 
      cases. SS may be excised before the correct diagnosis is made. CASE PRESENTATION: 
      we present a case involving a 4-year-old boy who visited our service with 
      complaints of left knee pain and limited knee flexion. Initially, the child was 
      diagnosed with osteochondromatosis. Surgical excision was opted, and initial 
      histopathological examination revealed a fibrous histiocytoma. The slide and 
      blocks were then brought to the King Faisal Specialist Hospital Research Center 
      (KFSH&RC) and histopathologic analysis has shown a well-circumscribed nodule in 
      the synovium with a sub-synovial monomorphic spindle cell sarcoma, confirmed by 
      fluorescence in situ hybridization (FISH). CONCLUSIONS: Therefore, we strongly 
      recommend considering all differential diagnoses for soft-tissue masses when 
      planning surgical management.
FAU - Al-Mohrej, Omar A
AU  - Al-Mohrej OA
AUID- ORCID: 0000-0001-6694-5443
AD  - Department of Orthopaedics, King Faisal Specialist Hospital and Research Centre, 
      Riyadh, Saudi Arabia. mohrejo@gmail.com.
FAU - Al-Jarallah, Saeed A
AU  - Al-Jarallah SA
AD  - Department of Orthopaedics, King Faisal Specialist Hospital and Research Centre, 
      Riyadh, Saudi Arabia.
FAU - Al-Dakhil Allah, Hamad H
AU  - Al-Dakhil Allah HH
AD  - Department of Orthopaedics, King Faisal Specialist Hospital and Research Centre, 
      Riyadh, Saudi Arabia.
FAU - Pant, Rajeev
AU  - Pant R
AD  - Department of Orthopaedics, King Faisal Specialist Hospital and Research Centre, 
      Riyadh, Saudi Arabia.
FAU - Al-Zayed, Zayed S
AU  - Al-Zayed ZS
AD  - Department of Orthopaedics, King Faisal Specialist Hospital and Research Centre, 
      Riyadh, Saudi Arabia.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200507
PL  - England
TA  - BMC Musculoskelet Disord
JT  - BMC musculoskeletal disorders
JID - 100968565
SB  - IM
MH  - Child, Preschool
MH  - Diagnosis, Differential
MH  - *Diagnostic Errors
MH  - Follow-Up Studies
MH  - Histiocytoma, Benign Fibrous/*diagnosis
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Knee Joint/pathology/surgery
MH  - Male
MH  - Osteochondromatosis/*diagnosis
MH  - Range of Motion, Articular
MH  - Sarcoma, Synovial/*diagnosis/surgery
MH  - Soft Tissue Neoplasms/*diagnosis/surgery
MH  - Treatment Outcome
PMC - PMC7206690
OTO - NOTNLM
OT  - Case report
OT  - Misdiagnosis
OT  - Pediatrics
OT  - Synovial sarcoma
COIS- The authors declare that there is no conflict of interest regarding the 
      publication of this paper.
EDAT- 2020/05/10 06:00
MHDA- 2021/02/02 06:00
PMCR- 2020/05/07
CRDT- 2020/05/09 06:00
PHST- 2020/03/28 00:00 [received]
PHST- 2020/04/23 00:00 [accepted]
PHST- 2020/05/09 06:00 [entrez]
PHST- 2020/05/10 06:00 [pubmed]
PHST- 2021/02/02 06:00 [medline]
PHST- 2020/05/07 00:00 [pmc-release]
AID - 10.1186/s12891-020-03312-3 [pii]
AID - 3312 [pii]
AID - 10.1186/s12891-020-03312-3 [doi]
PST - epublish
SO  - BMC Musculoskelet Disord. 2020 May 7;21(1):283. doi: 10.1186/s12891-020-03312-3.