PMID- 32382341
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1792-1074 (Print)
IS  - 1792-1082 (Electronic)
IS  - 1792-1074 (Linking)
VI  - 19
IP  - 6
DP  - 2020 Jun
TI  - Analysis of post-operative efficacy and pharyngeal fistula healing in patients 
      with laryngeal cancer treated with post-operative enteral nutrition support 
      nursing combined with early oral feeding.
PG  - 3964-3970
LID - 10.3892/ol.2020.11503 [doi]
AB  - The present study aimed to analyze the effects of post-operative enteral 
      nutrition support nursing combined with early oral feeding on post-operative 
      efficacy and pharyngeal fistula (PF) healing in patients with laryngeal cancer 
      (LC). A retrospective analysis of 133 patients with LC, who underwent 
      laryngectomy between May 2014 and September 2016, was conducted. Of these 
      patients, 61 patients (control group) were treated with enteral nutrition support 
      nursing combined with nasogastric feeding, and 72 patients (observation group) 
      were treated with enteral nutrition support nursing combined with early oral 
      feeding. Levels of serum albumin (ALB), pre-albumin (PA), hemoglobin (Hb) and the 
      lymphocyte count (LYM) were compared before and after surgery (7 and 14th 
      post-operative days). The post-operative weight, upper arm muscle circumference 
      (UAMC), triceps skinfold (TSF), post-operative infection, adverse reactions and 
      PF healing were also measured. No differences were observed between the control 
      and observation groups before surgery (all P>0.05). ALB, Hb, PA and LYM were 
      significantly decreased in the control group on the 7 and 14th days 
      post-operatively compared with those in the observation group (all P<0.05). Five 
      patients in the control group presented with PF during treatment, and seven 
      patients in the observation group suffered from PF after surgery. No difference 
      in the average healing time of PF, number of patients with post-operative 
      infection and adverse reactions were observed between the two groups (all 
      P>0.05). The weight and UAMC in the observation group, 14 days post-operatively, 
      were significantly higher than those before surgery in the same patients and in 
      the control group (all P<0.05), whereas no difference in TSF (P>0.05) was 
      observed. No differences in weight, UAMC and TSF were revealed in the control 
      group before surgery and on the 14th day post-operatively (all P>0.05). Thus, 
      post-operative enteral nutrition support nursing combined with early oral feeding 
      resulted in significant improvement in the post-operative efficacy of patients 
      with LC and had no effect on PF healing.
CI  - Copyright: (c) Lin et al.
FAU - Lin, Aitao
AU  - Lin A
AD  - Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated 
      Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, P.R. China.
FAU - Ye, Jin
AU  - Ye J
AD  - Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated 
      Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, P.R. China.
FAU - Wang, Zhiyuan
AU  - Wang Z
AD  - Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated 
      Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, P.R. China.
FAU - Li, Pei
AU  - Li P
AD  - Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated 
      Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20200401
PL  - Greece
TA  - Oncol Lett
JT  - Oncology letters
JID - 101531236
PMC - PMC7202300
OTO - NOTNLM
OT  - LC
OT  - PF
OT  - enteral nutrition support
OT  - oral feeding
EDAT- 2020/05/10 06:00
MHDA- 2020/05/10 06:01
PMCR- 2020/04/01
CRDT- 2020/05/09 06:00
PHST- 2018/10/23 00:00 [received]
PHST- 2019/12/31 00:00 [accepted]
PHST- 2020/05/09 06:00 [entrez]
PHST- 2020/05/10 06:00 [pubmed]
PHST- 2020/05/10 06:01 [medline]
PHST- 2020/04/01 00:00 [pmc-release]
AID - OL-0-0-11503 [pii]
AID - 10.3892/ol.2020.11503 [doi]
PST - ppublish
SO  - Oncol Lett. 2020 Jun;19(6):3964-3970. doi: 10.3892/ol.2020.11503. Epub 2020 Apr 
      1.