PMID- 32387396
OWN - NLM
STAT- MEDLINE
DCOM- 20210826
LR  - 20210826
IS  - 1872-7697 (Electronic)
IS  - 0167-8760 (Linking)
VI  - 153
DP  - 2020 Jul
TI  - Resting EEG effective connectivity at the sources in developmental dysphonetic 
      dyslexia. Differences with non-specific reading delay.
PG  - 135-147
LID - S0167-8760(20)30088-X [pii]
LID - 10.1016/j.ijpsycho.2020.04.021 [doi]
AB  - Previous studies conducted on subjects with dysphonetic dyslexia (DD) reported 
      inefficient timing integration of information from various brain areas. This 
      dysregulation has been referred as neuronal dyschronia or timing deficiency. The 
      present study examines the effective brain connectivity in Dysphonetic Dyslexic 
      subjects (DD) compared to a group of subjects with non-specific reading delay 
      (NSRD). The hypothesis is that the timing defect should be reflected also in the 
      effective connectivity and the subjects with developmental dyslexia have an 
      altered information flow different from the group of children with non-specific 
      reading delay. The quantitative EEG at the sources of 184 children with DD was 
      compared with that of 43 children with NRSD. The Isolated Effective Coherence 
      (iCoh) was calculated among 17 brain regions data driven selected. To assess 
      statistical differences in the EEG connectivity between the two groups, a Linear 
      Mixed Effect (LME) model was applied. Two very important areas perform as hubs in 
      the information flow: one is the left calcarine sulcus, which is more active in 
      the DD group. The second is the left rolandic operculum, which is more active in 
      the NSRD group. In the DD group, the calcarine sulcus is sending information to 
      the right postcentral gyrus, the left paracentral gyrus, the right angular gyrus 
      and the right supplementary motor area. This flow of information occurs in almost 
      all frequency bands, including delta and theta band. Slow connections may 
      indicate less efficient or even pathological information flow. We consider this 
      as a neurophysiological evidence of Boder's model of dyslexia.
CI  - Copyright (c) 2020. Published by Elsevier B.V.
FAU - Bosch-Bayard, Jorge
AU  - Bosch-Bayard J
AD  - McGill Centre for Integrative Neuroscience (MCIN), Ludmer Centre for 
      Neuroinformatics and Mental Health, Montreal Neurological Institute (MNI), McGill 
      University, Montreal, Canada. Electronic address: jorge.boschbayard@mcgill.ca.
FAU - Girini, Katia
AU  - Girini K
AD  - Centro Internazionale dei disturbi di apprendimento, attenzione e iperattivita, 
      (CIDAAI), Milano 20125, Italy.
FAU - Biscay, Rolando Jose
AU  - Biscay RJ
AD  - Centro de Investigacion en Matematicas. A.C., Jalisco S/N, Col. Valenciana, 
      Guanajuato 36023, Mexico.
FAU - Valdes-Sosa, Pedro
AU  - Valdes-Sosa P
AD  - The Clinical Hospital of Chengdu Brain Sciences Institute, University of 
      Electronic Science and Technology of China UESTC, Chengdu, China; Cuban 
      Neuroscience Center, Cuba.
FAU - Evans, Alan C
AU  - Evans AC
AD  - McGill Centre for Integrative Neuroscience (MCIN), Ludmer Centre for 
      Neuroinformatics and Mental Health, Montreal Neurological Institute (MNI), McGill 
      University, Montreal, Canada.
FAU - Chiarenza, Giuseppe Augusto
AU  - Chiarenza GA
AD  - Centro Internazionale dei disturbi di apprendimento, attenzione e iperattivita, 
      (CIDAAI), Milano 20125, Italy. Electronic address: 
      giuseppe.chiarenza@fastwebnet.it.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20200505
PL  - Netherlands
TA  - Int J Psychophysiol
JT  - International journal of psychophysiology : official journal of the International 
      Organization of Psychophysiology
JID - 8406214
SB  - IM
MH  - Brain Waves/physiology
MH  - Cerebral Cortex/*physiopathology
MH  - Child
MH  - *Connectome/methods
MH  - Developmental Disabilities/*physiopathology
MH  - Dyslexia/*physiopathology
MH  - *Electroencephalography/methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Nerve Net/*physiopathology
MH  - *Reading
OTO - NOTNLM
OT  - Dysphonetic dyslexia
OT  - Effective connectivity
OT  - Non-specific reading delay
OT  - Unleakage
OT  - Unmixing
OT  - qEEG
EDAT- 2020/05/11 06:00
MHDA- 2021/08/27 06:00
CRDT- 2020/05/11 06:00
PHST- 2020/02/03 00:00 [received]
PHST- 2020/04/21 00:00 [revised]
PHST- 2020/04/24 00:00 [accepted]
PHST- 2020/05/11 06:00 [pubmed]
PHST- 2021/08/27 06:00 [medline]
PHST- 2020/05/11 06:00 [entrez]
AID - S0167-8760(20)30088-X [pii]
AID - 10.1016/j.ijpsycho.2020.04.021 [doi]
PST - ppublish
SO  - Int J Psychophysiol. 2020 Jul;153:135-147. doi: 10.1016/j.ijpsycho.2020.04.021. 
      Epub 2020 May 5.