PMID- 32389047 OWN - NLM STAT- MEDLINE DCOM- 20210310 LR - 20210310 IS - 2047-9980 (Electronic) IS - 2047-9980 (Linking) VI - 9 IP - 10 DP - 2020 May 18 TI - Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015. PG - e014846 LID - 10.1161/JAHA.119.014846 [doi] LID - e014846 AB - Background No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long-term survival rates. Methods and Results We utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database from the National Cancer Institute for all PMCTs diagnosed between 1973 and 2015. From a total of 7 384 580 cases of cancer registered in SEER, we identified 327 men and 367 women with PMCTs. The majority (78%) of patients were white. Sarcoma was the most common type of PMCT in both men and women ( approximately 60%). Individuals diagnosed with lymphoma exhibited better survival than those with other types of PMCTs. Men were diagnosed at a younger age than women; however, there was no significant difference in overall survival between the sexes. Men diagnosed with PMCT between the ages of 51 and 65 years demonstrated prolonged survival compared with those diagnosed at younger or older ages. There was no difference in survival rates among women based on age at diagnosis. Conclusions PMCTs are rare in both men and women. Tumors tend to be diagnosed at an earlier age in men compared with women, but there is no sex disparity in survival rate. Sarcoma is the most common type of PMCT, and lymphoma is associated with the highest survival rate among both sexes. FAU - Antwi-Amoabeng, Daniel AU - Antwi-Amoabeng D AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Meghji, Zahara AU - Meghji Z AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Thakkar, Samarthkumar AU - Thakkar S AD - Department of Internal Medicine Rochester General Hospital Rochester NY. FAU - Ulanja, Mark B AU - Ulanja MB AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Taha, Mohamed AU - Taha M AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. AD - Department of Internal Medicine University of Iowa Hospitals and Clinics Iowa City IA. FAU - Adalja, Devina AU - Adalja D AD - Department of General Medicine Gotri Medical Education and Research Center Vadodara Gujarat India. FAU - Al-Khafaji, Jaafar AU - Al-Khafaji J AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Gullapalli, Nageshwara AU - Gullapalli N AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Beutler, Bryce D AU - Beutler BD AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. FAU - Boampong-Konam, Killian AU - Boampong-Konam K AD - Ghana Airport Clinc Limited Kotoka Internal Airport P.M.B KIA Accra Ghana. FAU - Doshi, Rajkumar AU - Doshi R AD - Department of Internal Medicine University of Nevada Reno School of Medicine Reno NV. LA - eng PT - Comparative Study PT - Journal Article DEP - 20200510 PL - England TA - J Am Heart Assoc JT - Journal of the American Heart Association JID - 101580524 SB - IM CIN - J Am Heart Assoc. 2020 May 18;9(10):e016032. PMID: 32389052 MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Databases, Factual MH - Early Detection of Cancer MH - Female MH - Health Status Disparities MH - Heart Neoplasms/diagnosis/*epidemiology/mortality MH - Humans MH - Male MH - Middle Aged MH - Prevalence MH - Risk Assessment MH - Risk Factors MH - SEER Program MH - Sex Factors MH - Time Factors MH - United States/epidemiology MH - Young Adult PMC - PMC7660836 OTO - NOTNLM OT - Surveillance, Epidemiology, and End Results OT - cardiac tumors OT - malignancy OT - sex OT - survival rate EDAT- 2020/05/12 06:00 MHDA- 2021/03/11 06:00 PMCR- 2020/05/18 CRDT- 2020/05/12 06:00 PHST- 2020/05/12 06:00 [pubmed] PHST- 2021/03/11 06:00 [medline] PHST- 2020/05/12 06:00 [entrez] PHST- 2020/05/18 00:00 [pmc-release] AID - JAH34869 [pii] AID - 10.1161/JAHA.119.014846 [doi] PST - ppublish SO - J Am Heart Assoc. 2020 May 18;9(10):e014846. doi: 10.1161/JAHA.119.014846. Epub 2020 May 10.