PMID- 32394733 OWN - NLM STAT- MEDLINE DCOM- 20210917 LR - 20220503 IS - 1540-2010 (Electronic) IS - 1540-2002 (Print) IS - 1540-2002 (Linking) VI - 19 IP - 3 DP - 2021 May-Jun TI - Perceived Stress, Subjective, and Objective Symptoms of Disturbed Sleep in Men and Women with Stable Heart Failure. PG - 363-377 LID - 10.1080/15402002.2020.1762601 [doi] AB - Objective/Background: Sleep disturbance is prevalent among patients with heart failure (HF) and is associated with increased morbidity and mortality. Stress also affects health and quality of life among patients with cardiovascular disease and likely plays a prominent role in HF. However, little is known about the associations between stress and sleep among HF patients.Participants: One hundred fifty-three stable New York Heart Association (NYHA) Classification I-IV HF patients with at least low symptoms of insomnia (M(age):63.0 +/- 12.8, 42% Women).Methods: We examined baseline stress, sleep disturbance, and sleep-related characteristics from a randomized controlled trial of cognitive behavioral therapy for insomnia, including the Perceived Stress Scale, Insomnia Severity Index, Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Sleep Disturbance Questionnaire, Dysfunctional Beliefs about Sleep Scale, PROMIS Cognitive Ability, SF-36 Mental Health, and wrist actigraphy. We used Pearson correlations and general linear models to assess stress-sleep associations, including the potential moderating effects of sex and symptom severity (NYHA).Results: There were moderate-to-large correlations between stress and self-reported sleep disturbance, dysfunctional beliefs about sleep, cognitive ability, and mental health (p's < 0.01). High stress was associated with more objectively-measured (i.e., actigraph-assessed) awakenings and sleep fragmentation among women than men (beta = - 0.04, p < 0.01; beta = - 0.71, p = 0.04). Relationships between stress and objectively-measured sleep did not vary by symptom severity.Conclusions: Perceived stress is related to sleep disturbance among HF patients, and effects may be sex-dependent. Subsequent research should determine the temporal links between sleep and stress, and optimal opportunities for intervention among HF patients. FAU - Gaffey, Allison E AU - Gaffey AE AUID- ORCID: 0000-0002-2960-2772 AD - Department of Internal Medicine (Cardiovascular Medicine), Yale School of Medicine, New Haven, Connecticut. AD - VA Connecticut Healthcare System, West Haven, Connecticut. FAU - Jeon, Sangchoon AU - Jeon S AUID- ORCID: 0000-0003-2855-2053 AD - Yale School of Nursing, Orange, Connecticut. FAU - Conley, Samantha AU - Conley S AUID- ORCID: 0000-0002-4501-5244 AD - Yale School of Nursing, Orange, Connecticut. FAU - Jacoby, Daniel AU - Jacoby D AUID- ORCID: 0000-0002-9182-275X AD - Department of Internal Medicine (Cardiovascular Medicine), Yale School of Medicine, New Haven, Connecticut. FAU - Ash, Garrett I AU - Ash GI AUID- ORCID: 0000-0002-8655-7525 AD - VA Connecticut Healthcare System, West Haven, Connecticut. AD - Department of Internal Medicine (General), Yale School of Medicine, New Haven, Connecticut. FAU - Yaggi, Henry K AU - Yaggi HK AD - VA Connecticut Healthcare System, West Haven, Connecticut. AD - Department of Internal Medicine (Pulmonary, Critical Care, and Sleep Medicine), Yale School of Medicine, New Haven, Connecticut. FAU - O'Connell, Meghan AU - O'Connell M AD - Yale School of Nursing, Orange, Connecticut. FAU - Linsky, Sarah J AU - Linsky SJ AUID- ORCID: 0000-0002-4204-7881 AD - Yale School of Nursing, Orange, Connecticut. FAU - Redeker, Nancy S AU - Redeker NS AUID- ORCID: 0000-0001-7817-2708 AD - Yale School of Nursing, Orange, Connecticut. LA - eng GR - R01 NR016191/NR/NINR NIH HHS/United States GR - UL1 TR001863/TR/NCATS NIH HHS/United States GR - K24 HL132093/HL/NHLBI NIH HHS/United States GR - P20 NR014126/NR/NINR NIH HHS/United States GR - R21 NR011387/NR/NINR NIH HHS/United States PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural DEP - 20200512 PL - England TA - Behav Sleep Med JT - Behavioral sleep medicine JID - 101149327 SB - IM MH - Aged MH - Female MH - *Heart Failure/epidemiology MH - Humans MH - Male MH - Middle Aged MH - *Sleep Initiation and Maintenance Disorders/epidemiology/psychology MH - *Stress, Psychological/psychology PMC - PMC7658015 MID - NIHMS1593558 EDAT- 2020/05/13 06:00 MHDA- 2021/09/18 06:00 PMCR- 2022/05/01 CRDT- 2020/05/13 06:00 PHST- 2020/05/13 06:00 [pubmed] PHST- 2021/09/18 06:00 [medline] PHST- 2020/05/13 06:00 [entrez] PHST- 2022/05/01 00:00 [pmc-release] AID - 10.1080/15402002.2020.1762601 [doi] PST - ppublish SO - Behav Sleep Med. 2021 May-Jun;19(3):363-377. doi: 10.1080/15402002.2020.1762601. Epub 2020 May 12.