PMID- 32395518 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220830 IS - 2305-5839 (Print) IS - 2305-5847 (Electronic) IS - 2305-5839 (Linking) VI - 8 IP - 7 DP - 2020 Apr TI - Interaction between delivery mode and maternal age in predicting overweight and obesity in 1,123 Chinese preschool children. PG - 474 LID - 10.21037/atm.2020.03.128 [doi] LID - 474 AB - BACKGROUND: Pediatric overweight/obesity has escalated to epidemic proportions worldwide. In this study, we aimed to assess the association of delivery mode and maternal age, both individually and interactively, with the risk of being overweight or obese among Chinese preschool children. METHODS: We cross-sectionally recruited 1,123 preschool children from five kindergartens in Beijing. Data were collected by a pre-validated self-developed questionnaire. Overweight and obesity are defined according to the World Health Organization (WHO), International Obesity Task Force (IOTF), and China criteria, respectively. RESULTS: Cesarean delivery was significantly associated with pediatric overweight/obesity under the WHO [adjusted odds ratio (aOR), 95% confidence interval (CI): 1.60, 1.12-2.29], IOTF (1.77, 1.23-2.53), and China (1.43, 1.06-1.94) criteria, respectively. Maternal age <28 years reached statistical significance under both WHO (1.69, 1.09-2.61) and IOTF (1.69, 1.09-2.61) criteria in predicting pediatric overweight/obesity. The interaction between cesarean delivery and maternal age <28 years was remarkably significant under the WHO (2.26, 1.10-4.67), IOTF (2.92, 1.43-5.96), and China (2.36, 1.24-4.50) criteria. CONCLUSIONS: Our findings indicate that the interaction between cesarean delivery and maternal age <28 years can remarkably increase the risk of overweight/obesity among Chinese preschool children. CI - 2020 Annals of Translational Medicine. All rights reserved. FAU - Liu, Shufang AU - Liu S AD - Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China. AD - Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China. FAU - Lei, Jieping AU - Lei J AD - Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China. AD - National Clinical Research Center for Respiratory Diseases, Beijing 100029, China. FAU - Ma, Jia AU - Ma J AD - Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China. AD - Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China. FAU - Ma, Yanyan AU - Ma Y AD - Department of Children's Health Care, Beijing Chaoyang District Maternal and Child Health Care Hospital, Beijing 100026, China. FAU - Wang, Shunan AU - Wang S AD - Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China. AD - Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China. FAU - Yuan, Yuan AU - Yuan Y AD - Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China. AD - Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China. FAU - Shang, Yu AU - Shang Y AD - Department of Children's Health Care, Beijing Chaoyang District Maternal and Child Health Care Hospital, Beijing 100026, China. FAU - Zhang, Zhixin AU - Zhang Z AD - Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China. AD - International Medical Services, China-Japan Friendship Hospital, Beijing 100029, China. FAU - Niu, Wenquan AU - Niu W AD - Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China. LA - eng PT - Journal Article PL - China TA - Ann Transl Med JT - Annals of translational medicine JID - 101617978 PMC - PMC7210148 OTO - NOTNLM OT - Delivery mode OT - maternal age OT - obesity OT - overweight OT - preschool children COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.03.128). The authors have no conflicts of interest to declare. EDAT- 2020/05/13 06:00 MHDA- 2020/05/13 06:01 PMCR- 2020/04/01 CRDT- 2020/05/13 06:00 PHST- 2020/05/13 06:00 [entrez] PHST- 2020/05/13 06:00 [pubmed] PHST- 2020/05/13 06:01 [medline] PHST- 2020/04/01 00:00 [pmc-release] AID - atm-08-07-474 [pii] AID - 10.21037/atm.2020.03.128 [doi] PST - ppublish SO - Ann Transl Med. 2020 Apr;8(7):474. doi: 10.21037/atm.2020.03.128.