PMID- 32395981 OWN - NLM STAT- MEDLINE DCOM- 20210618 LR - 20210618 IS - 1948-7193 (Electronic) IS - 1948-7193 (Linking) VI - 11 IP - 10 DP - 2020 May 20 TI - Nothing Ventured, Nothing Gained: Regulations Cripple Potentially Life-Saving Research of Illicit Substances. PG - 1382-1384 LID - 10.1021/acschemneuro.0c00241 [doi] AB - Modern day research, in an attempt to determine the potential therapeutic and adverse effects of illicit substances, is a growing field, but one that faces many regulatory challenges. Due to the potential abuse of illicit substances such as Cannabis, 3,4-methylenedioxymethamphetamine (MDMA), lysergic acid diethylamide (LSD) and psilocybin, regulations have been conceived with the intent of preventing harm and addiction. However, these regulations have also become a major barrier for the scientific community as they suffocate attempts of the scientists to acquire illicit substances for research purposes. Therefore, it is imperative to modify the current regulations of drug scheduling, leading to a reclassification of illicit substances that would allow for extensive testing in research settings. This reclassification effort could advance the potentially life-saving research of illicit substances. FAU - Abbott, Kodye L AU - Abbott KL AD - Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, Alabama 36849, United States. AD - Auburn University Research Initiative in Cancer, Auburn University, Auburn, Alabama 36849, United States. FAU - Gill, Kristina S AU - Gill KS AD - University of Massachusetts Memorial Medical Center, Worcester, Massachusetts 01655, United States. FAU - Flannery, Patrick C AU - Flannery PC AD - Rocky Vista University College of Osteopathic Medicine, Parker, Colorado 80134, United States. FAU - Boothe, Dawn M AU - Boothe DM AD - Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, Alabama 36849, United States. AD - Auburn University Research Initiative in Cancer, Auburn University, Auburn, Alabama 36849, United States. FAU - Dhanasekaran, Muralikrishnan AU - Dhanasekaran M AD - Auburn University Research Initiative in Cancer, Auburn University, Auburn, Alabama 36849, United States. AD - Department of Drug Discovery and Development, Auburn University, Auburn Alabama 36849, United States. FAU - Pondugula, Satyanarayana R AU - Pondugula SR AD - Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, Alabama 36849, United States. AD - Auburn University Research Initiative in Cancer, Auburn University, Auburn, Alabama 36849, United States. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200512 PL - United States TA - ACS Chem Neurosci JT - ACS chemical neuroscience JID - 101525337 RN - 0 (Hallucinogens) RN - 2RV7212BP0 (Psilocybin) RN - 8NA5SWF92O (Lysergic Acid Diethylamide) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - *Hallucinogens/therapeutic use MH - Humans MH - Lysergic Acid Diethylamide MH - *N-Methyl-3,4-methylenedioxyamphetamine MH - Psilocybin MH - *Substance-Related Disorders/drug therapy OTO - NOTNLM OT - Drug abuse OT - LSD OT - MDMA OT - cannabis OT - drug interactions OT - drug scheduling EDAT- 2020/05/13 06:00 MHDA- 2021/06/22 06:00 CRDT- 2020/05/13 06:00 PHST- 2020/05/13 06:00 [pubmed] PHST- 2021/06/22 06:00 [medline] PHST- 2020/05/13 06:00 [entrez] AID - 10.1021/acschemneuro.0c00241 [doi] PST - ppublish SO - ACS Chem Neurosci. 2020 May 20;11(10):1382-1384. doi: 10.1021/acschemneuro.0c00241. Epub 2020 May 12.