PMID- 32397944 OWN - NLM STAT- MEDLINE DCOM- 20210819 LR - 20210819 IS - 1557-8976 (Electronic) IS - 0882-8245 (Linking) VI - 33 IP - 8 DP - 2020 Oct TI - Prevalence of Porcine Pseudorabies Virus and Its Coinfection Rate in Heilongjiang Province in China from 2013 to 2018. PG - 550-554 LID - 10.1089/vim.2020.0025 [doi] AB - Pseudorabies (PR) is a highly contagious disease affecting a wide range of animals, which annually causes great economic losses in China. In this study, a total number of 18,815 serum samples and 1,589 tissue samples were collected from 311 intensive pig farms (>/=350 sows) located in eight cities in Heilongjiang province, and tested by ELISA and PCR. Overall, the serum positive rates of gE and gB protein were 16.3% and 84.5%, respectively. The PCR-positive rate of PR virus (PRV) in tissue samples was 17.8%. The coinfection rates of PRV with porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), and classical swine fever virus (CSFV) were also measured. The rate of PRV coinfected with PRRSV was 36.0% followed by 12.9% with PCV2 and 1.8% with CSFV, respectively. These results clearly demonstrate PRV prevalence and its coinfection rate in Heilongjiang province, indicating high PR endemic in pig farms in this region. This study provides data for further epidemiological investigations and a reference for developing PRV control strategies in this region and in China. FAU - Zhou, Han AU - Zhou H AD - College of Veterinary Medicine, Northeast Agricultural University, Heilongjiang, China. FAU - Pan, Yan AU - Pan Y AD - Animal Health and Diagnostic Center of CP Group, Heilongjiang, China. FAU - Liu, Mengda AU - Liu M AD - Laboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China. FAU - Han, Zifeng AU - Han Z AD - Emergency Centre for the Control of Transboundary Animal Diseases, Food and Agriculture Organization of the United Nations (FAO), Beijing, China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200512 PL - United States TA - Viral Immunol JT - Viral immunology JID - 8801552 RN - 0 (Antibodies, Viral) SB - IM MH - Animals MH - Antibodies, Viral/*blood MH - China/epidemiology MH - Circoviridae Infections/epidemiology/*veterinary MH - Classical Swine Fever Virus/pathogenicity MH - Coinfection/*epidemiology/*veterinary/virology MH - Cross-Sectional Studies MH - Farms/statistics & numerical data MH - Female MH - Herpesvirus 1, Suid/genetics/immunology/*pathogenicity MH - Pseudorabies/*epidemiology/immunology/virology MH - Seroepidemiologic Studies MH - Swine/virology MH - Swine Diseases/epidemiology/immunology/virology OTO - NOTNLM OT - Heilongjiang province OT - coinfection rate OT - pseudorabies virus OT - veterinary epidemiology EDAT- 2020/05/14 06:00 MHDA- 2021/08/20 06:00 CRDT- 2020/05/14 06:00 PHST- 2020/05/14 06:00 [pubmed] PHST- 2021/08/20 06:00 [medline] PHST- 2020/05/14 06:00 [entrez] AID - 10.1089/vim.2020.0025 [doi] PST - ppublish SO - Viral Immunol. 2020 Oct;33(8):550-554. doi: 10.1089/vim.2020.0025. Epub 2020 May 12.